healthcare innovation summit 2016

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Jul 02nd
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March of Dimes, UHG Launch Prenatal Care Program to Help Improve Health Outcomes  (22.06.2016)

UnitedHealth Group contributes $700,000 to help launch and evaluate new group prenatal care program for pregnant women
New program aims to reduce nation's preterm birth rate to 5.5 percent by 2030 from the 2015 rate of 9.6 percent
 
March of Dimes and UnitedHealth Group are launching a new group prenatal care program designed to help improve mothers' and babies' health during pregnancy, birth and infancy.
 
March of Dimes supportive pregnancy care enables expectant mothers to access prenatal care on a monthly basis in a supportive group setting with women who are of similar gestational ages. During each visit, expectant mothers will have more time with their care providers than they would during their standard individual prenatal checkups, and benefit from prenatal care education and vital social and emotional support from other mothers. This environment can empower women to take control of their pregnancy care and fosters relationships that can last throughout their pregnancies and beyond.
 
Funded by $700,000 from UnitedHealth Group, March of Dimes and UnitedHealth Group will collaborate to develop the program's content and curriculum, and make it available to participating care providers. The curriculum will adhere to the prenatal care standards of the American College of Obstetricians and Gynecologists.
 
March of Dimes will operate the program in Tennessee beginning fourth-quarter 2016. The program will include web-based tools and a social media platform to enable mothers to connect and socialize with each other online outside the group sessions and access helpful information on healthy pregnancies. The program will be open to any expecting mother interested in participating, regardless of insurance coverage.
 
March of Dimes and UnitedHealth Group will evaluate the program's performance over the coming months to build a case study with a goal to expand the model to more care providers and health systems across the country.
 
"Preterm birth takes a devastating toll on the health of families in the United States and costs the health care system billions," said March of Dimes President Dr. Jennifer L. Howse. "And for the first time in eight years, the national preterm birth rate has increased rather than decreased. Preterm birth continues to be the No. 1 killer of babies. We must redouble our efforts to prevent the serious lifelong health consequences that many babies suffer from being born too soon. Our enhanced group prenatal care program could help change this dynamic, one mother and child at a time. We are pleased to work with UnitedHealth Group to accelerate the adoption of group prenatal care that can make a positive difference in so many lives."
 
Dr. Deneen Vojta, a pediatrician and executive vice president at UnitedHealth Group's Enterprise Research and Development, said: "group prenatal care is part of the future of care for expecting mothers and their babies because it's about creating emotional and social support, motivation and education to have a healthy birth and baby. We are grateful for the opportunity to collaborate with March of Dimes to put mothers and babies on the path to better health and reduce health care costs."
 
The Toll of Preterm Births in the United States
According to the National Center for Health Statistics (NCHS), nearly 10 percent of all births in the United States are preterm, meaning these babies are born before 37 weeks of pregnancy. That represents one of the highest prematurity rates of any developed country in the world. The March of Dimes 2015 Premature Birth Report Card shows serious disparities continue to exist among communities and among racial and ethnic groups in the United States, with African-American infants more than twice as likely to be born preterm as white infants.
 
The economic costs of preterm births reached $26.2 billion in 2006 – the most recent data available from the Institute of Medicine – accounting for more than one-third of all U.S. health care spending for infants, according to the Institute of Medicine. A premature birth costs employers about 10 times more than a healthy, full-term birth in the first year of life ($55,393 vs. $5,085), according to a 2014 analysis by Truven Health Analytics commissioned by the March of Dimes.
Babies who survive an early birth often have lifelong health issues such as cerebral palsy, vision and hearing loss, and intellectual disabilities. Even infants born just a few weeks early have a greater risk of respiratory distress syndrome (RDS), feeding difficulties, temperature instability (hypothermia), jaundice and delayed brain development.
 
Group prenatal care has gained momentum in recent years and has shown promising evidence that it can lead to healthier pregnancies and births, and lay the foundation for better lifelong health. In addition to providing substantially more contact with health care providers, prenatal care delivered in a group setting can motivate pregnant women to be more actively engaged in their health care, offer support services, and meet the needs of pregnant women and their families more effectively.
 
Research from the National Institutes of Health (NIH) found that a group setting for prenatal care was associated with fewer preterm births, reduced incidence of low-birth-weight infants, and shorter neonatal intensive care unit (NICU) stays after birth. States and the federal government bear a substantial share of the costs of preterm birth through the Medicaid program, which covers roughly half of all births. The potential net savings to the Medicaid program over a five-year period would equal roughly $12 billion if half the pregnant women enrolled in Medicaid were to receive care through a group model, according to research from the UnitedHealth
 
Center for Health Reform & Modernization.
Successfully scaling this program is expected to improve population health outcomes, reduce disparities and decrease systemwide costs. March of Dimes' goal for the program is to reduce the nation's preterm birth rate to 5.5 percent by 2030 from the 2015 preliminary NCHS rate of 9.6 percent.
 
About March of Dimes
The March of Dimes is the leading nonprofit organization for pregnancy and baby health. For more than 75 years, moms and babies have benefited from March of Dimes research, education, vaccines, and breakthroughs. For the latest resources and health information, visit our websites marchofdimes.org and nacersano.org. If you have been affected by prematurity or birth defects, visit our shareyourstory.org community to find comfort and support. For detailed national, state and local perinatal statistics, visit persistats.org. You can also find us onFacebook or follow us on Twitter.
 
About UnitedHealth Group
UnitedHealth Group is a diversified health and well-being company dedicated to helping people live healthier lives and helping to make the health system work better for everyone. UnitedHealth Group offers a broad spectrum of products and services through two distinct platforms: UnitedHealthcare, which provides health care coverage and benefits services; and Optum, which provides information and technology-enabled health services. For more information, visit UnitedHealth Group at www.unitedhealthgroup.com .

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Astellas Pharma Inc Ties Up with University of Tokyo on Rice-Based Vaccine (22.06.2016)
The Institute of Medical Science, the University of Tokyo and Astellas Pharma Inc. announced that they have signed a new collaborative development agreement on the rice-based oral vaccine “MucoRice-CTB” (“MucoRice”) against cholera*1 and enterotoxigenicEscherichia coli (E coli) *2 caused diarrheal diseases.
 
MucoRice is a rice-based oral vaccine expressing cholera toxin B subunit (CTB)*3 in the intrinsic storage protein of rice using genetic engineering, which was developed by Prof. Hiroshi Kiyono, Project researcher Yoshikazu Yuki and their colleagues at International Research Development Center for Mucosal Vaccines (IMSUT).
 
In developing countries, diarrhea caused by pathogenic bacteria such as Vibrio cholerae and enterotoxigenic E coli, is one of the major causes of death among infants. At present, the challenges of the cholera vaccines used in developing countries are the need for the cold chain*4 and the ineffectiveness against enterotoxigenic E coli.MucoRice is stable at room temperature and easily produced, therefore it is expected to meet the unmet medical needs of existing cholera vaccines.
 
Under the MEXT (Ministry of Education, Culture, Sports, Science and Technology) and the AMED (Japan Agency for Medical Research and Development) Translational Research Network Program, an investigator-initiated phase 1 trial of this vaccine is nearing completion at IMSUT hospital (Principal investigator, Assoc. Prof. Osamu Hosono) in Japan. Data from this trial is now being analyzed.
 
Under the contract, IMSUT provides clinical trial materials and trial data, etc. which are necessary for the phase 1 and phase 2 trials of MucoRice for cholera and enterotoxigenic E coli., and Astellas is responsible for conducting and managing the clinical trials.
 
Through the collaborative development, IMSUT and Astellas will develop vaccines against infectious diseases affecting developing countries and hope we can address Access to Health issues.
 
*1Cholera:
Cholera is an acute gastroenteritis by Vibrio cholera which produce cholera toxin causing severe diarrhea. It is spread through contaminated food or water, therefore it is more common in developing countries.
*2Enterotoxigenic Escherichia coli:
Enterotoxigenic E coli is the E coli which produces a toxin that causes diarrhea and abdominal pain in humans. Severe diarrhea is caused by ingesting food or water contaminated by it. It is common in areas that lacks an adequate environmental sanitation, responsible for diarrhea in infants, and is also known to be a major cause of diarrhea in tourists who visit these areas.
*3Cholera toxin B subunit (CTB):
Cholera toxin consists of 2 types of subunits, CTA (chorea toxin A subunit) is toxic, and CTB pentamer adheres to epithelial cells and delivers CTA into the cell.
*4The cold chain:
The cold chain is a system to store and transport vaccine at a constant low temperature to maintain its effect.
 
About Access to Health issues:
There are many people with insufficient access to healthcare they need due to the lack of available treatments, poverty, challenges in healthcare systems and limited healthcare information. Astellas recognizes this problem as “Access to Health” issue and works to improve “Access to Health” by engaging in various initiatives.
 
About the Institute of Medical Science, the University of Tokyo
The Institute of Medical science, the University of Tokyo (IMSUT) was founded by Prof. Shibasaburo Kitasato in 1892 as “The Institute of Infectious Disease”. IMSUT with its own affiliated hospital is Japan's foremost university-associated research institute for medical and life science. Focusing on infectious disease, cancer and immunological diseases, our mission is to translate basic research findings directly to novel medical therapies. Thus, research environment of IMSUT is represented by the "bed to bench and bench to bed" inheriting the Kitasato’s DNA of “Wisdom and Practice” for medical science leading to the next generation of Genome-based medicine, Antibody-drugs, .Mucosal Vaccines, Gene-therapy and Regenerative medicine.
 
About Astellas
Astellas Pharma Inc., based in Tokyo, Japan, is a company dedicated to improving the health of people around the world through the provision of innovative and reliable pharmaceutical products. We focus on Urology, Oncology, Immunology, Nephrology and Neuroscience as prioritized therapeutic areas while advancing new therapeutic areas and discovery research leveraging new technologies/modalities. We are also creating new value by combining internal capabilities and external expertise in the medical/healthcare business. Astellas is on the forefront of healthcare change to turn innovative science into value for patients. For more information, please visit our website at www.astellas.com/en.

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Amgen Sponsors QB3953 Incubator For Life Science Startups (21.06.2016)
Amgen announced a five-year, platinum sponsorship of the QB3@953 life sciences incubator to accelerate the development of new therapies to improve human health. The shared laboratory space at QB3@953 was created to help high-potential life science and biotech startups overcome a key obstacle for many early stage organizations - access to laboratory infrastructure.

As part of the sponsorship, Amgen launched two "Amgen Golden Ticket" awards, providing each winner with one year of lab space at the QB3@953 life sciences incubator, additional facility benefits and connections to Amgen's scientific and business leaders.

The 2016 Amgen Golden Ticket winners, Mission Bio and SiteOne Therapeutics, were chosen by a team of scientific leaders who evaluated the strength and novelty of the scientific rationale, subject matter expertise, and business plan viability.

"The QB3@953 Amgen Golden Ticket award supports our research and development strategy to fund early-stage innovation in the biotech hubs of San Francisco and Cambridge, Massachusetts," said Flavius Martin, vice president of Research, Inflammation and Oncology at Amgen. "It's critical to the future of healthcare to support promising scientific entrepreneurs. It's rewarding to be part of the energy and enthusiasm of scientific entrepreneurs in this early stage, and to help accelerate the momentum of advancements in human health."

Amgen also supports the LabCentral incubator adjacent to Amgen's Cambridge Research and Development center.
"We are delighted to facilitate the connection with Amgen, one of the world's leading biotechnology companies, with the entrepreneurs at QB3@953," said Doug Crawford, managing director at QB3@953.  "Being chosen as the Amgen Golden Ticket winner brings a prestige that resonates with the scientific community in addition to the lab resources, scientific and business expertise that Amgen provides." 

"The leadership and scientists of SiteOne Therapeutics are honored to receive the Amgen Golden Ticket award," saidJohn Mulcahy, co-founder and vice president of research at SiteOne Therapeutics. "The vision and entrepreneurial spirit of Amgen is remarkable, both in helping to provide resources to innovative new companies like ours, and in continuing to fuel development of cutting-edge medicines and research through programs like the Amgen Golden Ticket. We are proud to have the significance of our science and the work that we are doing to develop novel therapeutics for chronic and acute pain without the danger and side effects of opioids recognized by such a strong leader in the biopharmaceutical industry."

"The Amgen Golden Ticket award will accelerate our development of high throughput single-cell genomic applications in immuno-oncology," said Charlie Silver, CEO at Mission Bio. "We are excited by this partnership with Amgen, which will offer support for extending our platform into applications that have high potential for clinical impact."

About Amgen
Amgen is committed to unlocking the potential of biology for patients suffering from serious illnesses by discovering, developing, manufacturing and delivering innovative human therapeutics. This approach begins by using tools like advanced human genetics to unravel the complexities of disease and understand the fundamentals of human biology.

Amgen focuses on areas of high unmet medical need and leverages its expertise to strive for solutions that improve health outcomes and dramatically improve people's lives. A biotechnology pioneer since 1980, Amgen has grown to be one of the world's leading independent biotechnology companies, has reached millions of patients around the world and is developing a pipeline of medicines with breakaway potential. 
For more information, visit www.amgen.com  

CONTACT: 
Amgen, San Francisco
Carol Pawlak, (650) 244-2325


Douglas Crawford
(415) 633-6151
This e-mail address is being protected from spam bots, you need JavaScript enabled to view it

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June 2016 - PDF | e-book

Discussing about Digitalization in Healthcare & it's benefits have never been more important earlier.

With this in mind, we introduce the latest edition of Hospital & Healthcare Management - Vol 5 Issue 3 your one-stop resource that hepls you stay up to date with the issues that matters most.

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