Philips and Illumina join forces to offer integrated genomics solutions for oncology





Royal Philips , a global leader in health technology, and Illumina, Inc. the global leader in DNA sequencing and array-based technologies, today announced a strategic collaboration, that aims to integrate Illumina’s sequencing systems for large-scale analysis of genetic variation and function and  Philips’ IntelliSpace Genomics clinical informatics platform, and to coordinate  marketing and sales of the resulting solutions. Philips and Illumina will also seek  to engage in clinical research collaborations with health systems in the US who  want to develop precision medicine programs in oncology.

Profiling tumors  using genomic information is critical for complex cancer cases, and next-generation  DNA sequencing – the process of rapidly profiling large sections of the genome  in parallel to find mutations – is increasingly being used for this. However, challenges  remain in developing ways to rapidly and accurately interpret genomic findings  in the context of a patient’s condition. While cancer patients can have hundreds  of gene variants in their tumors, only a small number may actually drive the  individual’s specific cancer or may have actionable therapeutic implications  for a particular patient. The patient’s history, related lab tests and cancer  type are needed for a meaningful interpretation of the genomic data.

Philips and  Illumina will collaborate to provide new solutions aimed at the acquisition, analysis,  annotation and interpretation of genomics data in oncology cases. The data will  be acquired by Illumina’s BaseSpace® Sequence Hub connected to its instruments and will be processed  through Philips’ IntelliSpace Genomics solution for oncology. This solution will combine data from  multiple sources – radiology, immunohistochemistry, digital pathology, medical  records and lab tests – and will deliver a consolidated dashboard view. This  system will support researchers to develop insights more efficiently and will  ultimately support lowering the cost of health care delivery and improved  health outcomes.

“The value of  genomic information for personalized care, and for the treatment of patients  with cancer in particular, is tremendous,” said Jeroen Tas, CEO of Connected  Care and Health Informatics at Philips. “Until now the ability to use genomic  data with the aim of having a precise diagnosis of cancer and improve treatment  was mostly for the domain of academic centers. Through this collaboration we will  unlock the value of genomics for a much wider group of laboratories and care providers  to help them advance genomics initiatives at greater speed with the aim to offer  precision medicine with better outcomes for their patients.”

“We believe that this collaboration will provide an  excellent path for our next-generation sequencing systems to be incorporated  into health systems in the U.S. and worldwide,” said Francis deSouza, President  and CEO of Illumina. “One key strategy in our commitment to improving human  health is connecting genomics to the everyday business of healthcare: based on  integrated patient data, embedded into clinical pathways, supported by  real-world evidence and reimbursement models.”

The two companies intend to collaborate on system  integration, cohort analysis and health economics applications, and future  research programs. Laboratories adopting the solution will be able to integrate  sequencing data with information from multiple data sources (e.g., imaging,  pathology and laboratory). The Illumina-Philips solution will also give them ready  access to advanced analytics, deep learning technologies and available  reference literature, guidelines, and evidence in a single view.

IntelliSpace Genomics is powered by Philips HealthSuite, a secure,  cloud-enabled ecosystem of systems, clinical applications and digital tools  that gives access to advanced capabilities such as universal big data  management, predictive analytics, artificial intelligence and Internet of  Things (IoT) to support clinicians in first-time-right decision support. This enables Philips IntelliSpace Genomics to deliver real-time, actionable  information to physicians and specialists for therapy planning, across locations.

BaseSpace® Sequence Hub is a cloud-based platform that seamlessly extends Illumina  instruments for the acquisition and analysis of genomic data, and managing sequencing  runs and Illumina sequencing platforms to optimize operations. It enables the  sharing of genomic data with a broad range of value-added Illumina and  ecosystem analysis applications.

About Royal Philips
Royal Philips is a leading health technology company focused on improving people’s health and enabling better outcomes across the health continuum from healthy living and prevention, to diagnosis, treatment and home care. Philips leverages advanced technology and deep  clinical and consumer insights to deliver integrated solutions. Headquartered  in the Netherlands, the company is a leader in diagnostic imaging, image-guided  therapy, patient monitoring and health informatics, as well as in consumer  health and home care. Philips’ health technology portfolio generated 2015 sales  of EUR 16.8 billion and employs approximately 70,000 employees with sales and  services in more than 100 countries. News about Philips can be found at www.philips.com/newscenter .

About Illumina
Illumina is improving human health by unlocking the  power of the genome. Our focus on innovation has established us as the global  leader in DNA sequencing and array-based technologies, serving customers in the research, clinical, and applied markets. Our products are used for applications in the life sciences, oncology, reproductive health, agriculture, and other emerging segments. To learn more, visit www.illumina.com

Steve Klink
Philips Group Communications
Tel.: +31 6 10888824
E-mail: steve.klink@philips.com

Kathy O’Reilly
Philips Group Communications
Tel: +1 978-221-8919
E-mail: Kathy.Oreilly@Philips.com