NuVasive Launches Modulus ALIF 3D-Printed Porous Titanium Implant for Anterior Spine Surgery


NuVasive, Inc., the leader in spine technology innovation, focused on transforming spine surgery with minimally disruptive, procedurally integrated solutions, announced the commercial launch of Modulus® ALIF, a 3D-printed porous titanium implant for anterior lumbar interbody fusion (ALIF), in targeted global regions.

“Modulus ALIF has been one of NuVasive’s most successful clinical evaluations to date with continued surgeon adoption and overwhelmingly positive feedback. This differentiated technology furthers our position to become the market leader in ALIF and extends our Modulus portfolio across all procedural segments,” said Massimo Calafiore, executive vice president, Global Business Units at NuVasive. “We are leveraging our experience as the leader in lateral surgery to deliver outcome-driven innovation to fuel continued growth and differentiation in the anterior spine segment.”

Modulus ALIF is the latest addition to the NuVasive Advanced Materials Science® (AMS) portfolio and provides implants and instrumentation designed for both supine ALIF and XALIF™ procedures. In addition, Modulus ALIF comes in a variety of sizes and lordotic options to accommodate varying patient anatomy. Highlights of the Modulus ALIF technology include:

Proprietary Modulus titanium design: Modulus is designed for enhanced osseointegration,1 biomechanical,1 and imaging properties. The porous surface architecture is engineered to participate in fusion and promote new bone on-growth and in-growth.2 The proprietary design also allows for enhanced visualization compared to solid titanium implants.

Zero-step locking mechanism: This feature provides definitive tactile and visual confirmation, enabling confidence in a surgeon’s screw placement in the implant.

Low-profile, versatile instrumentation: The device’s instrumentation can be utilized in both supine ALIF and XALIF, supporting a surgeon’s preferred surgical approach. The instrumentation’s low-profile and versatile features are designed to increase operating room workflow efficiencies.

“Modulus ALIF has been a long awaited implant in my practice. The design is best-in-class and the differentiated surface structure will help improve fusion and clinical outcomes,” said Gregory M. Mundis Jr., M.D., orthopedic spine surgeon and co-director of the San Diego Spine Fellowship at Scripps Health in San Diego. “The device’s instrumentation is designed to work with various patient anatomies. This versatility makes me more confident that I am choosing the best solution for my patients.”

NuVasive is committed to furthering innovation and clinical validation of X360®, a comprehensive lateral approach to single-position surgery that includes XLIF®, XALIF, and XFixation™. Recently, a new journal article was published in World Neurosurgery that further validates the improved benefits possible with single-position surgery compared to dual-position lumbar fusion. The findings concluded that shorter operating time and hospital stays were more prevalent in single-position surgery while maintaining similar clinical outcomes.

NuVasive will feature Modulus ALIF at these upcoming events:

NuVasive Innovation Event: A surgeon-focused event today, July 22, where NuVasive leadership and surgeon partners will discuss NuVasive’s outcome-driven innovation including Modulus ALIF, the Pulse® platform, C360®, and more. Visit for more information.

37th Annual Meeting of the Section on Disorders of the Spine and Peripheral Nerves: On Thursday, July 29, NuVasive will host a lunch workshop discussing patient-specific care with NuVasive’s ALIF, XALIF, and AMS portfolio of implants. Visit NuVasive at booth #301 where it will also feature the Pulse platform, X360, and the Simplify® Cervical Disc.

About NuVasive
NuVasive, Inc. is the leader in spine technology innovation, with a mission to transform surgery, advance care, and change lives. The Company’s less-invasive, procedurally integrated surgical solutions are designed to deliver reproducible and clinically proven outcomes. The Company’s comprehensive procedural portfolio includes surgical access instruments, spinal implants, fixation systems, biologics, software for surgical planning, navigation and imaging solutions, magnetically adjustable implant systems for spine and orthopedics, and intraoperative neuromonitoring technology and service offerings. With more than $1 billion in net sales, NuVasive has approximately 2,700 employees and operates in more than 50 countries serving surgeons, hospitals, and patients.