Close

CABG Outcomes in Diabetics With LV Dysfunction

Note* - All images used are for editorial and illustrative purposes only and may not originate from the original news provider or associated company.

Subscribe

- Never miss a story with notifications

- Gain full access to our premium content

- Browse free from any location or device.

Media Packs

Expand Your Reach With Our Customized Solutions Empowering Your Campaigns To Maximize Your Reach & Drive Real Results!

– Access the Media Pack Now

– Book a Conference Call

– Leave Message for Us to Get Back

Related stories

WHO Supplies Medical Equipment for Post-Marburg Virus Heal

In a recent move, the World Health Organization has...

Life Sciences Sector Plan Sets UK on Global Growth Track

Main Article: UK Life Sciences Sector Plan Sets Sights...

UK Government Launches Ambitious Life Sciences Sector Plan

Government Unveils Life Sciences Roadmap for Growth and Innovation London,...

Highly Customized Treatments to Offer Specialized Care to UK

The Human Medicines Regulations 2025, which came into force...

What are the long-term results of percutaneous coronary intervention (PCI) and coronary artery bypass grafting (CABG) in patients with coronary artery disease (CAD), diabetes mellitus (DM), and left ventricular dysfunction (LVD)?

Methods:
The investigators used a propensity-matched study to compare outcomes for patients with CAD, DM, and LVD treated with PCI or CABG between 2004 and 2016. This registry study of patients cared for in Alberta, Canada of 110,000 included 2,387 patients. The primary outcome was major adverse cardiac and cerebrovascular events (MACCE) defined as the composite of death, stroke, myocardial infarction (MI), and repeat revascularization. Secondary outcomes were the individual components of the primary outcome.

Results:
PCI as compared with CABG was associated with a higher risk of MACCE in both the ejection fraction (EF) 35-49% (p < 0.001) and EF <35% (p < 0.001) cohorts. Treatment with PCI was associated with an increased risk of death in both the EF 35-49% and the EF <35% cohorts. Stroke rate did not differ between PCI and CABG in either EF cohort. PCI was associated with an increased rate of MI in the EF <35% cohort and repeat revascularization occurred more frequently in those treated with PCI in both the EF 35-49% cohort and the EF <35% cohort.

Conclusions:
The authors concluded that at long-term follow-up, patients with CAD, DM, and LVD treated with CABG exhibited a significantly lower incidence of MACCE and better long-term survival over PCI, without a higher risk of stroke.

Perspective:
This study reports that in both moderate and severe LVD, PCI is associated with an increased risk of MACCE when compared to CABG. Furthermore, in patients with CAD, DM, and moderate or severe LVD, PCI is associated with poorer long-term survival compared to CABG. Also of note, there was no significant difference in incidence of stroke between PCI and CABG in both the moderate and severe LVD cohorts. Based on this and other available data, CABG should be considered first-line therapy for the treatment of multivessel CAD in patients with DM and LVD.

Latest stories

Related stories

WHO Supplies Medical Equipment for Post-Marburg Virus Heal

In a recent move, the World Health Organization has...

Life Sciences Sector Plan Sets UK on Global Growth Track

Main Article: UK Life Sciences Sector Plan Sets Sights...

UK Government Launches Ambitious Life Sciences Sector Plan

Government Unveils Life Sciences Roadmap for Growth and Innovation London,...

Highly Customized Treatments to Offer Specialized Care to UK

The Human Medicines Regulations 2025, which came into force...

Subscribe

- Never miss a story with notifications

- Gain full access to our premium content

- Browse free from any location or device.

Media Packs

Expand Your Reach With Our Customized Solutions Empowering Your Campaigns To Maximize Your Reach & Drive Real Results!

– Access the Media Pack Now

– Book a Conference Call

– Leave Message for Us to Get Back