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CVS Health launches Symphony to support senior safety at home and enhance caregiver peace of mind

CVS Health launches Symphony to support senior safety at home and enhance caregiver peace of mind

CVS Health recently introduced the Symphony medical alert system to help caregivers monitor the safety and well-being of loved ones, even from afar.

This collection of in-home and wearable devices offers a new at-home experience by connecting a suite of sensors that can monitor for falls, motion, and room temperature while also providing a 24/7 personal emergency response platform for use when needed. Symphony is designed to support the growing number of seniors choosing to maintain an independent lifestyle at home, as well as those involved in their care.

“We’re committed to helping consumers on their path to better health and new consumer health innovations like Symphony can help give caregivers peace of mind as they monitor a loved one’s safety and well-being through a truly differentiated connected health approach,” said Adam Pellegrini, SVP of Enterprise Virtual Care & Consumer Health at CVS Health.

The center of the Symphony ecosystem is the voice-activated Smart Hub which enables hands-free calls with caregivers or emergency responders, while also monitoring motion, temperature, and air quality within the home.

Symphony features a free app for caregivers that provides alerts for falls or other emergencies and assists with facilitating care coordination. Additionally, smart algorithms within the app track and alert caregivers when normal conditions, such as average room temperature or air quality, are disrupted, suggesting when the caregiver may want to check in with their loved one.

Designed to fit a family’s specific needs and adapt to a variety of homes, two easy-to-use Symphony device options are available: the Basic Bundle and Essential Bundle. While both systems come equipped with the Smart Hub and a wearable care button, the Essential Bundle also includes motion sensors and a voice-activated Fall Sensor to automatically detect falls in the bathroom, where the majority of accidents occur. Complementary devices are available for both bundles if desired, including additional motion sensors to extend the range of coverage in larger homes, and entry sensors for use on doors, cabinets or windows.

Pricing starts at $149.99 for the Symphony Basic Bundle and $249.99 for the Essential Bundle. A monthly service fee is required, although no long-term contract is needed to activate. Once activated, each Symphony bundle can help support safety at home as well as in the event of an emergency. Customers can find Symphony available now at CVS HealthHUB® locations or online at cvs.com/symphony.

About CVS Health

CVS Health is a different kind of health care company. We are a diversified health services company with nearly 300,000 employees united around a common purpose of helping people on their path to better health. In an increasingly connected and digital world, we are meeting people wherever they are and changing health care to meet their needs. Built on a foundation of unmatched community presence, our diversified model engages one in three Americans each year. From our innovative new services at HealthHUB® locations, to transformative programs that help manage chronic conditions, we are making health care more accessible, more affordable and simply better.

CVS Health collaborates with Cancer Treatment Centers of America to provide in-home chemotherapy

CVS Health collaborates with Cancer Treatment Centers of America to provide in-home chemotherapy

CVS Health announced it is working with Cancer Treatment Centers of America® (CTCA) to increase access to chemotherapy at home for eligible, fully insured patients. Together, the companies are focused on minimizing patient exposure to COVID-19 from inpatient or hospital outpatient settings during the ongoing pandemic while ensuring continuity of critical cancer care. The program leverages Coram’s home infusion capabilities, coupled with training in chemotherapy administration based on Oncology Nursing Society guidelines, harnessing CTCA’s expertise as a top oncology care provider to give patients who may have delayed their care due to COVID-19 the flexibility to receive treatment from the safety and comfort of home.

“The COVID-19 pandemic has created new challenges for immunocompromised patients with cancer looking for ways to safely continue their care, while minimizing their exposure to the virus,” said Sree Chaguturu, M.D., Chief Medical Officer of CVS Caremark and CVS Specialty. “This collaborative arrangement with Cancer Treatment Centers of America allows us to combine our unique expertise in home infusion and clinical oncology to help more patients access treatment from the safety of their home.”

Clinically eligible and fully insured CTCA patients with a range of cancers, including breast cancer, lung cancer, prostate cancer, colorectal cancer, head and neck cancers, and some genitourinary cancers on particular chemotherapy/immunotherapy medications, will begin their first cycles of infused chemotherapy in the hospital or outpatient care center, and, if tolerated over a number of months, can be transitioned home for continued infusions. Once home, patients will receive in-home Coram nurse visits to administer the therapy, paired with regular telehealth visits and digital therapeutic check-ins with their CTCA clinician, care team, pharmacists and other clinical staff as needed. More information is available at www.cancercenter.com/oncology-clinic-at-home.

“Putting patients first has been our philosophy for over 30 years, and working together with CVS is an extension upon in which we can better meet their needs, especially in light of a pandemic. For a variety of reasons, COVID-19 has caused far too many people to skip or delay treatments. We’re seeing a 50% reduction in infusions, and, while a slight delay in treatments may have been appropriate at the pandemic’s onset, data is now pointing to increased mortality risk with every month of delayed care,” said Dr. Chevon M. Rariy, M.D., CTCA telehealth program director. “We’re proud to be working with Coram to provide home infusion of cancer treatment that prioritizes the safety of patients, their families and health care workers.”

In collaboration with CTCA and their approach to quality, safe care, coupled with more than 35 years of infusion expertise, Coram has the ability to reach 97 percent of the U.S. population. The program is being piloted in the Atlanta market and will expand to other geographies over the next few months to help increase access to important home-based cancer care during and beyond the pandemic. More information on the steps that CVS Health is taking to address the COVID-19 pandemic is available at the company’s frequently updated COVID-19 resource center.

About CVS Health

CVS Health is a different kind of health care company. We are a diversified health services company with nearly 300,000 employees united around a common purpose of helping people on their path to better health. In an increasingly connected and digital world, we are meeting people wherever they are and changing health care to meet their needs. Built on a foundation of unmatched community presence, our diversified model engages one in three Americans each year. From our innovative new services at HealthHUB locations, to transformative programs that help manage chronic conditions, we are making health care more accessible, more affordable and simply better. Learn more about how we’re transforming health at www.cvshealth.com.
About Cancer Treatment Centers of America

Cancer Treatment Centers of America® (CTCA) is a national oncology network of hospitals and outpatient care centers offering an integrated approach that combines surgery, radiation, chemotherapy, immunotherapy and advancements in precision medicine with supportive therapies to manage side effects and enhance quality of life during treatment and into survivorship. CTCA® publishes treatment results bi-annually including patient experience, length of life, quality of life, patient safety and quality of care. CTCA also offers qualified patients a range of clinical trials that may reveal new treatment options supported by scientific and investigational research. CTCA patient satisfaction scores consistently rank among the highest for all cancer care providers in the country.

Virginia Behavioral Health Agency Selects Cerner to Enhance Care Coordination Across 12 Facilities

Cerner Simplifies Patient Communication

Cerner Corporation announced it will provide its electronic health record (EHR) to 12 behavioral health facilities across the Commonwealth of Virginia. This approach eases sharing of patient health records across all facilities within the Virginia Department of Behavioral Health and Developmental Services (DBHDS), which provides behavioral health and developmental disability resources to the state’s residents.

“As a trusted industry leader in technology, data exchange and interoperability, Cerner can deliver the efficiency, reliability and security our clients, including DBHDS, need to improve health outcomes,” said John Dreager, PhD, vice president of client relationships, Cerner. “Cerner’s technology is designed to help improve continuity of patient care and a seamless exchange of health data between doctors and patients. We are proud to help Virginia address the mental and behavioral health needs of their residents.”

A recent study published in the Journal of the American Medical Association finds a nearly 25% increase in depression symptoms in U.S. adults in 2020. This increased prevalence in depression symptoms could lead to a greater demand on behavioral health support organizations like DBHDS. With Cerner technology, 12 Virginia facilities will now be better equipped to provide more efficient and coordinated medical care for their communities. Access to data across facilities also helps health systems better understand opportunities for efficiencies and improvement in their organizations.

“A single EHR across all locations is a key step towards standardizing care delivery” said Alison Land, DBHDS Commissioner. “As the demand for community mental health and substance abuse resources continues to rise in the wake of the pandemic, there’s no better time to upgrade technology systemwide. For us this marks a new era of automation, bringing increased care coordination across our network and using technology to help improve care, treatment and communication with our clients.”

Cerner technology is currently in use at eight DBHDS facilities: Western State Hospital (Staunton), Southwestern Virginia Mental Health Institute (Marion), Southern Virginia Mental Health Institute (Danville), Commonwealth Center for Children & Adolescents (Staunton), Southeastern Virginia Training Center (Chesapeake), Eastern State Hospital (Williamsburg), Northern Virginia Mental Health Institute (Falls Church) and Catawba Hospital (Catawba). Four additional DBHDS facilities are on-track to deploy in Spring 2021.

Abbott to Launch the NeuroSphere myPath Digital Health App Designed to Track and Report Pain Relief in Chronic Pain Patients

Abbott to Launch the NeuroSphere myPath Digital Health App Designed to Track and Report Pain Relief in Chronic Pain Patients

Abbott announced the upcoming launch of NeuroSphere™ myPath™, a digital health app designed to track and report on patient perceived pain relief and general well-being associated with spinal cord stimulation (SCS) or dorsal root ganglion (DRG) therapy. During the device trial period required before the permanent implant, the app allows patients to record their outcomes on pain and well-being while trialing their neurostimulation therapy.

Abbott’s NeuroSphere myPath is a digital innovation that will provide relief to the millions of Americans currently living with chronic pain that are eligible for SCS or DRG therapy. This new digital health app will allow patients to use their Apple mobile device to connect with Abbott support, access educational resources and track the progress of their trial pain relief journey.

“The COVID-19 pandemic put a spotlight on the need for digital and remote health tools,” said Keith Boettiger, vice president, Neuromodulation, Abbott. “The launch of the NeuroSphere myPath is one more example of how Abbott has been leading the way in providing remote ways to connect doctors and patients. Patients will be able to see information on their phone that would typically only be accessible in a doctor’s office – helping patients to share their journey with their doctors.”

Prior to committing to full implantation of a neuromodulation device, patients undergo a trial period to test device capabilities and capacity for pain relief. During the trial, temporary leads are placed and connected to an external generator, allowing patients to experience firsthand the impact of neuromodulation on their chronic pain and related symptoms.

“The current digital healthcare landscape has revolutionized our ability to provide direct care for patients whenever they need,” said Shachi Patel, M.D., interventional pain management physician and owner of Delmarva Pain and Spine Center in Newark, Del. “By providing patients with a more seamless, easier way to record their progress during the trial period, Abbott’s NeuroSphere myPath app will enable an enhanced communication experience while providing patients with further insight on their overall outcomes and response to neuromodulation.”

NeuroSphere myPath is the latest innovation that fits within the company’s broader NeuroSphere Digital Care connected health management platform. NeuroSphere myPath will be compatible with Abbott’s Proclaim™ XR SCS System for patients living with chronic pain in the trunk and limbs, and Proclaim™ DRG Neurostimulation System for patients with chronic pain in the lower limbs caused by complex regional pain syndrome or causalgia.

“As clinicians, we are constantly in search of more intuitive tools and easy-to-use applications that enable us to provide better care for our patients living with chronic pain – particularly when trialing a new treatment,” said Pankaj Mehta, M.D., medical director, chief medical officer and director of research at Pain Specialists in Austin, Texas. “Assessing a patient’s response to a new stimulation therapy is essential to determining a therapeutic course-of-action. With Abbott’s NeuroSphere myPath app, I will have the ability to assess the information patients have been recording and provide a comprehensive assessment on how they are responding to the therapy.”

The NeuroSphere myPath will be available on the Apple App Store in the coming weeks and is expected to be available on Android devices in Q2 2021.

 

About Abbott’s Chronic Pain Portfolio
Chronic pain can negatively impact personal relationships, work productivity and a person’s daily routine. Abbott is a global leader in the development of chronic pain therapy solutions, offering radiofrequency therapy and spinal cord stimulation therapy solutions, including radiofrequency ablation generators and accessories, BurstDR™ stimulation, and dorsal root ganglion stimulation in the portfolio of chronic pain treatments.

About Abbott
Abbott is a global healthcare leader that helps people live more fully at all stages of life. Our portfolio of life-changing technologies spans the spectrum of healthcare, with leading businesses and products in diagnostics, medical devices, nutritionals and branded generic medicines. Our 107,000 colleagues serve people in more than 160 countries.

Tampa General Hospital And Kindred Healthcare Break Ground On New Inpatient Rehabilitation Hospital

Tampa General Hospital And Kindred Healthcare Break Ground On New Inpatient Rehabilitation Hospital

Tampa General Hospital and Kindred Healthcare, LLC broke ground on a freestanding 59-bed inpatient rehabilitation hospital in the medical district of downtown Tampa. Announced as a joint venture in May 2020, the new facility will help meet the growing needs of Tampa Bay, the region and the state for rehabilitation recovery and care.

“Rehabilitation care plays an important role in the recovery of patients who have experienced debilitating illnesses and injuries,” stated John Couris, president and CEO of Tampa General Hospital. “As part of our vision to be the safest and most innovative academic health system in America, we’re proud to partner with Kindred to employ the latest innovation and technology to enhance access to these crucial services.”

The new rehabilitation hospital is located on Kennedy Boulevard between Oregon Avenue and Willow Avenue and brings downtown Tampa one step further in the development of a fully realized medical district that will attract the best scientists and physicians to the region and transform the area into a center for healthcare innovation. The rehabilitation hospital is projected to be approximately 80,000 square feet and cost $35 million. Kindred will manage the day-to-day operations of the new hospital, which is projected to employ more than 140 caregivers and staff. Tampa General Hospital will provide medical support services, such as imaging, lab and surgical procedures. It is expected to officially open in February 2022.

Tampa General Hospital currently operates an inpatient rehab facility that is accredited by the Commission on Accreditation of Rehabilitation Facilities (CARF). Clinical teams will ultimately move to the new site, while Tampa General Hospital will continue to provide pediatric and outpatient rehabilitation at alternate sites.

A small, physically distant groundbreaking ceremony was held on January 18, 2021. In attendance were John Couris, president and CEO, Tampa General, Russ Bailey, president, Kindred Rehabilitation Services, and Cleve Haralson, vice president of capital development for Kindred Healthcare.

“Breaking ground on Kindred’s first freestanding inpatient rehabilitation hospital in Florida is a great way to start 2021,” said Russ Bailey, president, Kindred Rehabilitation Services. “Working together with Tampa General, we can bring a dedicated intensive rehabilitative facility to the Tampa Bay region that will help patients achieve their best possible recovery.”

The new inpatient rehabilitation hospital will care for adults recovering from conditions such as stroke, neurological disease, injury to the brain or spinal cord and other debilitating illnesses or injuries. The new facility will offer state-of-the-art technology and feature all private rooms. It will also have a secured brain injury unit with private dining and a therapy gym.

“The COVID-19 pandemic has underscored the need for inpatient rehabilitation services,” noted Couris. “Some patients need specialized help with ventilator recovery and rebuilding their strength and function. While we hope that the pandemic is not a major consideration at the time of opening the new rehabilitation hospital, it’s good for our region to know that we’re here to help when needed.”

Health Affairs Journal projects that 700,000 survivors of COVID-19-related hospitalization will require inpatient rehabilitative care. “We have the resources to help patients reduce disability and create the best opportunity for patients to achieve a full recovery,” said Bailey. “Tampa General’s long experience as a CARF-accredited rehabilitation hospital is an added benefit and will help establish our new facility as a strong resource for the community.”

Transitional living apartments designed to simulate a residential apartment will enable patients to heal in a personalized and private environment as they prepare to return to independent living. Patients will also experience specially planned rooms to treat dialysis patients and programs dedicated to neurological conditions, stroke, brain injury and amputation recovery.

ABOUT TAMPA GENERAL HOSPITAL
Tampa General Hospital, a 1006-bed non-profit academic medical center, is one of the largest hospitals in America and delivers world-class care as the region’s only center for Level l trauma and comprehensive burn care. Tampa General Hospital is the highest-ranked hospital in the market in U.S. News & World Report’s 2020-21 Best Hospitals, and one of the top four hospitals in Florida, with five specialties ranking among the best programs in the United States. It is one of the nation’s busiest adult solid organ transplant centers and is the primary teaching hospital for the USF Health Morsani College of Medicine. With five medical helicopters, Tampa General Hospital transports critically injured or ill patients from 23 surrounding counties to receive the advanced care they need. Tampa General houses a nationally accredited comprehensive stroke center and its 32-bed Neuroscience Intensive Care Unit is the largest on the West Coast of Florida. It also is home to the Jennifer Leigh Muma 82-bed Level IV neonatal intensive care unit, and a nationally accredited rehabilitation center. Tampa General Hospital’s footprint includes 17 Tampa General Medical Group Primary Care offices, TGH Family Care Center Kennedy, TGH Brandon Healthplex, TGH Virtual Health and 19 outpatient Radiology Centers. Tampa Bay residents also receive world-class care from the TGH Urgent Care powered by Fast Track network of clinics, and they can even receive home visits in select areas through TGH Urgent Care at Home, powered by Fast Track. As one of the largest hospitals in the country, Tampa General Hospital is first in Florida to partner with GE Healthcare and open a clinical command center that uses artificial intelligence and predictive analytics to improve and better coordinate patient care at a lower cost.

ABOUT KINDRED HEALTHCARE
Kindred Healthcare, LLC is a healthcare services company based in Louisville, Kentucky with annual revenues of approximately $2.7 billion(1). At September 30, 2020, Kindred through its subsidiaries had approximately 23,900 employees providing healthcare services in 327 locations in 35 states, including 64 long-term acute care (“LTAC”) hospitals, 22 inpatient rehabilitation hospitals, 10 sub-acute units, behavioral health services, and non-affiliated hospital-based rehabilitation services in 101 inpatient rehabilitation units and 130 LTAC hospitals, medical/surgical and outpatient therapy sites of service. Ranked as one of Fortune magazine’s Most Admired Healthcare Companies for nine years, Kindred’s mission is to help our patients reach their highest potential for health and healing with intensive medical and rehabilitative care through a compassionate patient experience.

 

Boston Children’s Hospital and Baystate Health Form Collaboration To Improve Access to Specialized Pediatric Care

Boston Children's Hospital and Baystate Health Form Collaboration To Improve Access to Specialized Pediatric Care

Boston Children’s Hospital and Baystate Health have formed a collaboration that will improve patient access to highly specialized pediatric care and strengthen the coordination of care between the hospitals.

The collaboration will provide patients throughout western Massachusetts with improved access to pediatric specialty care at Baystate Children’s Hospital, and it will streamline care planning among providers at Boston Children’s and Baystate Children’s. The collaboration anticipates the two hospitals will jointly develop pathways to ensure children and adolescents get the right care in the right setting. In some instances, Boston Children’s clinicians will be available to provide care at Baystate Children’s.

“As the leading children’s hospital in western Massachusetts, Baystate Children’s has long partnered with the community to advance the health and well-being of all children from prevention to critical care. Today we are delighted to build upon our exceptional care for families through a collaboration with the much-respected Boston Children’s Hospital, which will provide additional clinical expertise when needed for our young patients,” says Dr. Mark A. Keroack, president and CEO of Baystate Health.

Dr. Charlotte Boney, chair of the Department of Pediatrics at Baystate Children’s Hospital adds: “This collaboration acknowledges and strengthens the close working relationship with Boston Children’s Hospital that we have enjoyed for many years. This collaboration will facilitate our continued ability to keep specialty care local so that children and families have access to a broad range of high-quality, affordable services right here in western Massachusetts. We look forward to exploring other opportunities that will strengthen our collaboration to serve our mutual missions of patient care, medical education and community service.”

The collaboration builds on the strong working relationship that currently exists between the hospitals. The two hospitals already work collaboratively in cardiology, neurology and dermatology, and by enhancing medical education, remote consults, information technology and other initiatives, will be better able to coordinate care for their patients.

 

Bayer transforms pharma business through breakthrough innovation in healthcare

Innovaccer Launches Unified Patient Record to Deliver Complete View of the Patient

Bayer presented exciting progress in transforming its pharmaceutical business with breakthrough innovation in healthcare that will significantly help patients suffering from conditions that are currently still difficult to treat. The company has recently heavily invested in external innovation with an unprecedented number of more than 25 collaboration agreements and acquisitions.

“The biomedical and technological revolution that is transforming healthcare at an unprecedented pace is taking place now. Our company is at the forefront of the wave of innovation in cell and gene therapy as well as digital health,” said Stefan Oelrich, Member of the Board of Management, Bayer AG and President of Bayer’s Pharmaceuticals Division. “We are driving this transformation and growing our promising development portfolio together with our partners. Our joint goal is to bring breakthrough treatments to patients and make healthcare systems more sustainable in the mid- and long-term.”

At its virtual Pharma Media Day, speakers from Bayer, its partners and leading experts demonstrated under the theme “Transforming Healthcare. Transforming Bayer” how the company is committed to transforming patient health by fulfilling its strategic ambition in the areas of cell and gene therapy, digital health and by driving forward the company’s promising development portfolio.

Cell and Gene Therapy: Accelerating breakthrough innovation for patients

Cell and gene therapies offer for the first time the possibility to address the root cause of disease, providing options for conditions considered intractable or where the current standard of care only addresses symptoms to different degrees. Bayer’s increasing investments in the field are consolidating the company’s emerging leadership and confirm its strategic significance as a growth-driver for its pharmaceutical business.

Bayer has just established a new Cell and Gene Therapy Platform. This platform steers Bayer’s strategy in the area and orchestrates all activities along the value chain providing an innovation ecosystem for all partners, including BlueRock Therapeutics and Asklepios BioPharmaceutical (AskBio), two companies fully owned by Bayer but independently operated. Bayer’s development portfolio of cell and gene therapies already comprises seven advanced assets in different stages of clinical development. These are focused on multiple therapeutic areas with high unmet need, such as neurodegenerative, neuromuscular and cardiovascular indications, with leading programs in Pompe disease, Parkinson’s disease, hemophilia A, and congestive heart failure. With over fifteen preclinical assets in the cell and gene therapy field, the pipeline is expected to grow steadily year by year.

“Cell and gene therapies hold the promise to significantly impact patients’ lives by moving from treating symptoms to potentially curative approaches,” said Wolfram Carius, Executive VP and Head of Cell and Gene Therapy at Bayer. “Together with our partners, we want to accelerate innovation at its source and along the whole value chain to ensure a fast translation of science into therapies for patients who have no time to wait.”

BlueRock Therapeutics recently announced that the U.S. Food and Drug Administration (FDA) has cleared their Investigational New Drug application to proceed with a Phase I study in patients with advanced Parkinson’s disease. This will be the first trial in the United States to study pluripotent stem cell-derived dopaminergic neurons in patients with Parkinson’s disease and a big step forward for the stem cell field.

Digital Health: Empowering patients through Integrated Care

Digital healthcare offerings have become an important pillar of modern healthcare. The combination of conventional healthcare approaches with innovative digital technologies makes it possible to offer efficient solutions addressing the needs of a person in his/her specific environment. Bayer is developing Integrated Care concepts which offer individual support of patients. This personalized approach addresses complex and interconnected health challenges within the individual circumstances.

Integrated Care is a key element of Bayer’s digital business strategy in pharma. In collaboration, Bayer and the digital health company Informed Data Systems Inc. (IDS/One Drop) are expanding their business based on IDS’s existing diabetes management platform. This solution was downloaded more than 3 million times. Together, the companies are now creating new health offerings to address the needs of patients in the areas of cardiovascular diseases, women’s health and oncology. Experts from both companies are jointly working on the first two modules, which are to become available within a year.

“By focusing on the individual patient, not their disease, Integrated Care is the path to truly inclusive and personalized healthcare,” said Jeanne Kehren, Senior VP of Digital & Commercial Innovation and Member of the Pharmaceuticals Executive Committee of Bayer AG. “We are determined to make Integrated Care solutions a major pillar of our company’s pharmaceutical business. Building on our expertise in the pharmaceutical sector, we can bridge the gap between tech and healthcare. In the next ten years, we expect digital health offerings to significantly contribute to our revenues.”

Growing a robust pipeline: New approaches for unmet medical needs

Bayer is continuing to build a strong development pipeline advancing more than 50 projects through the clinic with a focus on cardiovascular diseases, oncology and women’s health. The company highlighted two promising pipeline programs in mid-stage development demonstrating medical innovation at Bayer.

As an innovation leader in cardiovascular diseases with deep disease understanding and a long history of successful drug development, Bayer is particularly strong in the field of anticoagulation. Heart attack and stroke still represent a major health burden and new, more effective treatment options in thrombosis prevention are needed. The company is advancing a promising mid-stage program of Factor XI (FXI)-targeting compounds, a new class of anticoagulants, comprising of three investigational assets. A small molecule oral FXIa-inhibitor has commenced a Phase IIb program (PACIFIC), planning to enroll more than 4,000 patients in total. In addition, an anti-FXIa antibody and a FXI-ligand-conjugated antisense oligonucleotide (FXI-LICA), which Bayer is developing under exclusive license from IONIS Pharmaceuticals, have recently started Phase II trials, in patients with end-stage kidney disease. FXI-pathway inhibition may offer protection from thromboembolic events without increased risk of bleeding. This may provide a treatment option to patients for whom currently no suitable therapeutic options are available.

With its P2X3 multi-indication program, Bayer highlighted another important candidate in mid-stage development. At Bayer, the promise of P2X3 antagonists was first identified for endometriosis within the company’s strategic research alliance with Evotec, a Germany-based drug discovery and development company. Endometriosis is a clinical condition affecting approximately 10 percent of women in reproductive age, many of whom experience severe chronic pain with debilitating effects on their professional, personal and social lives. P2X3 also has a prominent role in several other medical conditions associated with pain and neurogenic hypersensitivity such as chronic cough, overactive bladder and neuropathic pain. Although these diseases are not life-threatening, they severely impact the quality of life for a very large number of patients – and P2X3 antagonists could potentially offer a new treatment approach and relief to these patients. For its development strategy, Bayer decided to explore a novel path in research and development pursuing not one but multiple possible indications early on and in parallel in the clinic. As of today, Bayer has entered Phase IIb clinical trials for refractory and/or unexplained chronic cough, with a trial in endometriosis soon to follow. In addition, Phase IIa clinical studies have commenced for overactive bladder and diabetic neuropathic pain.

“Our research in the fields of Factor XI inhibitors and P2X3 antagonists are just two promising examples of mid-stage programs that demonstrate our ongoing commitment to building and advancing a strong development pipeline,” said Stefan Oelrich. “Positioning Bayer as a leader in the highly dynamic space of healthcare innovation, we will continue to lead the field in bringing new solutions to patients who need them.”

At the same time, the company is also successfully delivering on its late-stage pipeline in the areas of oncology and cardiovascular disease including also a number of potential blockbuster products. In the area of oncology, for example, darolutamide (jointly developed with Orion Corporation), a differentiated treatment option that extends survival for men with non-metastatic castration-resistant prostate cancer who are at high risk for developing metastatic disease (nmCRPC), and shows a favorable safety profile. The product has received regulatory approval in several markets, including the U.S., the European Union (EU), Brazil, Canada and Japan. The Phase III study ARASENS in the indication of metastatic hormone sensitive prostate cancer (mHSPC) is expecting data read-out in 2021. Larotrectinib is a first-in-class precision oncology treatment designed to treat patients with solid tumors harboring a Neurotrophic Tyrosine Receptor Kinase (NTRK) gene fusion (1). The product is approved in more than 40 countries, including the U.S. and countries of the EU. It was the first treatment in the EU to receive a tumor-agnostic indication.

Finerenone is an investigational first-in-class treatment for patients with chronic kidney disease (CKD) and type 2 diabetes (T2D), a condition of high unmet medical need and limited treatment options. Finerenone has been submitted for marketing approval in the US and in the EU based on Phase III data from the FIDELIO-DKD trial. The Phase III program with finerenone in CKD in T2D is the largest Phase III clinical trial program to date in CKD and T2D. It comprises two studies, evaluating the effect of finerenone versus placebo on top of standard of care on both renal and cardiovascular outcomes. The second Phase III trial in patients with CKD in T2D, FIGARO-DKD, is still ongoing. Vericiguat, which is being jointly developed with MSD (a tradename of Merck & Co., Inc., Kenilworth, NJ, USA), is currently under development for the treatment of patients with chronic heart failure and reduced ejection fraction (HFrEF). It could offer a specific mechanism of action to restore the functioning of a critical pathway, so far not addressed by current therapies. Vericiguat has been submitted for marketing authorization in the U.S., EU, Japan and China as well as multiple other countries. In July 2020, the FDA granted MSD’s application the status of priority review for the approval of vericiguat.

In the field of women’s healthcare, Bayer recently added a highly attractive asset to its development portfolio through the acquisition of KaNDy Therapeutics. BAY-342 (formerly NT-814) is a first in class, non-hormonal, once-daily, oral neurokinin-1,3 receptor antagonist for the treatment of vasomotor symptoms (hot flashes and night sweats) during menopause, planned to start Phase III development in 2021.

(1) Larotrectinib is the first precision oncology therapeutic of its kind to treat adult and pediatric patients with solid tumors that display an NTRK gene fusion, who have a disease that is locally advanced, metastatic or where surgical resection is likely to result in severe morbidity, and who have no satisfactory treatment options.

About Bayer
Bayer is a global enterprise with core competencies in the life science fields of health care and nutrition. Its products and services are designed to benefit people by supporting efforts to overcome the major challenges presented by a growing and aging global population. At the same time, the Group aims to increase its earning power and create value through innovation and growth. Bayer is committed to the principles of sustainable development, and the Bayer brand stands for trust, reliability and quality throughout the world. In fiscal 2019, the Group employed around 104,000 people and had sales of 43.5 billion euros. Capital expenditures amounted to 2.9 billion euros, R&D expenses to 5.3 billion euros.

Robocath successfully carries out Europe’s first remote robotic-assisted coronary angioplasty

Robocath, a company that designs, develops and commercializes cardiovascular robotic systems for the treatment of vascular diseases, today announces the successful completion of the first remote robotic-assisted coronary angioplasty in Europe. The procedure was carried out by Prof. Eric Durand and Prof. Rémi Sabatier at the Rouen Medical Training Center and Caen University Hospital in France – spanning 75 miles (120 km) between the two locations. The procedure is the first of its kind in Europe; it was completed with R-One™, Robocath’s first commercial robotic-assisted platform. This unprecedented achievement opens the door to new options for patients who live in remote areas and require swift treatment to successfully treat cardiovascular diseases.

The procedure was carried out on an animal model on December 8, 2020. Consistent communication between Prof. Sabatier – operating in the Caen University Hospital, and Prof. Durand – based at the Medical Training Center in Rouen, was secured using a variety of tools.

Prof. Rémi Sabatier, Interventional Cardiologist at Caen University Hospital and Associate Professor in Remote Medicine said: “There are still significant disparities in the level of care for cardiovascular diseases depending on where a patient lives. For example, in Europe, 40% of heart attacks are not treated with a coronary angioplasty, even when this is clearly a better option for the patient than fibrinolytic therapy. This is essentially because it takes too long to get to an interventional cardiology center (1). This pioneering robotic procedure, the first in Europe carried out at a distance of over 70 miles, could eventually improve patient care in case of serious cardiac events such as heart attacks and strokes, and save lives. Aside from the technical achievement, it’s been a privilege for me personally to be involved in this first intervention. The equipment provided by Robocath meant that I was perfectly able to communicate with my colleagues in Rouen without a hitch. Operating my tools remotely felt exactly the same as a standard robotic procedure.”

Prof. Eric Durand, Interventional Cardiologist at Rouen University Hospital said: “I’m delighted to have participated in this landmark operation, which has proven that long-distance robotic procedures can be completed safely and securely by qualified caregivers. There are a number of challenges that still need to be overcome before this can become commonplace within this sector, particularly in relation to the required personnel training and legal liability. Nonetheless, I’m convinced that the future of interventional cardiology is robotic and that this remote connection module will speed up growth in this area.”

Bruno Fournier, CTO at Robocath said: “This successful operation is a great proof-of-concept in a number of technical aspects; it demonstrates that a coronary angioplasty can be completed safely between two distant sites. In the long run, our goal is to provide the user with the same level of performance as with an in-person robotic procedure.”

Lucien Goffart, CEO of Robocath said: “Cardiovascular diseases are currently the number one cause of death worldwide. In part, this is due to a number of circumstances which make it hard to improve treatment, such as geographic, structural and economic factors. Ensuring equality of treatment and access to care – regardless of where one lives, is fundamental. Robotic interventional medicine unquestionably represents a reliable response to these major social challenges. Firstly, robotic procedures make vascular intervention safer for the physician, by providing complete protection from X-rays; over the last 15 years, X-ray exposure has had a significant effect on the number of qualified people entering this field. People are less available, less willing to train, because of the health conditions caused by wearing lead equipment. This has resulted in a growing shortage of qualified medical staff. Secondly, remote robotic interventions will provide patients with rapid access to the best treatment by experts, who can operate from a specialist center on a patient located at a smaller ER.”

Philippe Bencteux, President and Founder of Robocath said: “When I founded this company, almost ten years ago, my ambition was to develop robotic solutions for remote treatment in order to improve care for patients suffering from serious heart conditions such as strokes, heart attacks and hemorrhagic shocks. This telerobotic intervention represents a major triumph for public health. It will clear the way for better treatment for a significant majority of the population – who have not had access to it before. Almost twenty years after the first surgery was carried out between two different locations: New York and Strasbourg, I am particularly proud that Robocath has achieved this ‘first’ in remote vascular intervention. It is a key step in developing the field and will soon lead to a new global era in interventional treatment.”

Prime Minister Launches pan India rollout of COVID-19 vaccination drive

Johnson & Johnson to test single-shot coronavirus vaccine on 60,000 people in phase-3 trials

The Prime Minister, Narendra Modi launched the pan India rollout of Covid-19 vaccination drive via video conferencing.  This is the world’s largest vaccination program covering the entire length and breadth of the country. A total of 3,006 session sites across all States and UTs were virtually connected during the launch.

The Prime Minister started his speech by paying compliments to the scientists who were associated with the development of the vaccines. He said, usually it takes years to prepare a vaccine but here, in such a short time, not one but two made-in-India vaccine were launched. The Prime Minister cautioned the people to be careful about not missing taking two doses.

He said that there will be a gap of one month between the doses. He asked people to keep their guards up even after taking the vaccine as only two weeks after taking the second dose, human body will develop necessary immunity against corona.

The Prime Minister put the unprecedented scale of the vaccination drive in perspective by informing that, in the first round itself, 3 crore people, which is more than population of at least 100 countries of the world, are being vaccinated.

He said that this needs to be taken up to 30 crores in the second round when elderly and people with serious co-morbidities will be vaccinated. He said that there are only three countries- India, USA and China, who have the population of more than 30 crore.

The Prime Minister asked people not to give heed to rumours and conspiracy theories as Indian vaccine scientists, medical system, Indian process and institutional mechanism in this regard is trusted globally and this trust is earned with a consistent track record.

PM Modi congratulated the country for a united and brave fight against corona. He termed the Indian response to corona as one of self-confidence and self-reliance. He noted a determination of not to let the confidence weaken in every Indian. He dwelled at length on the contribution of doctors, nurses, para medical staff, ambulance drivers, ASHA workers, sanitation workers, police and other frontline workers who endangered their lives to save other. Some of them didn’t even return to their homes as they lost their lives in the fight against the virus, noted a solemn Prime Minister.

Recalling the initial days of the crisis, the Prime Minister noted that India showed alertness and took right decisions at the right moments. Two weeks before the first case, which was detected on 30th January 2020, India had formed High-Level Committee. India had started proper surveillance exactly one year ago from today. On 17th January 2020, India issued its first advisory and India was among the first nations to start screening of passengers at the airports.

The Prime Minister congratulated the countrymen to pass the challenge of discipline and patience during the Janata Curfew. He pointed out that the exercise prepared the country psychologically for the lockdown. Morale of the country was kept high with the campaigns like taali-thali and lighting of diya, the Prime Minister added.

Modi also talked about evacuation of Indians stuck abroad. In a time when many countries of the world had left their citizens stranded in China, India evacuated not only the Indians bit citizens of other countries. He recalled sending of entire lab to a country that was finding it difficult to test evacuating Indians.

The Prime Minister said India’s response to the crisis has been acknowledged globally. It was an example of the integrated and unified response from centre, states, local governments, government offices, social bodies who performed efficiently in unison, The Prime Minister concluded.

Mayo Clinic Laboratories and American Hospital Dubai Announce Strategic Partnership

Mayo Clinic Laboratories and American Hospital Dubai announce a strategic partnership aimed at improving advanced laboratory diagnostics in the Dubai region. Under the agreement, the two organizations will begin delivering laboratory testing through a collaboration based out of American Hospital Dubai in early 2021.

Sherif Beshara, Group CEO of American Hospital Dubai, commented, “We are excited to build upon the knowledge of Mayo Clinic Laboratories to deliver practice-defining diagnostics in the region.”

“Our goal for this relationship is to offer advanced laboratory testing to better help clinicians answer complex medical questions for their patients,” says William Morice II, M.D., Ph.D., president of Mayo Clinic Laboratories. “Effective laboratory diagnostics is critical to improving patient care, and, by bringing this service straight to the region, we are dramatically reducing test turnaround times.”

Mayo Clinic Laboratories and American Hospital Dubai also will work together to improve access to complex laboratory diagnostics for the region’s providers. By improving access to laboratory testing, health care providers will have the necessary tools to advance patient care.

Dr Paul Aoun, Head of Endocrinology and Director of the Mayo Clinic Liaison at the American Hospital Dubai, said, “The essence of this partnership is in line with the ‘union of forces’ spirit for the betterment of patients. This milestone achievement will help integrate the best available advancements in clinical diagnostics for the ultimate goal of improving patient care.”

“Laboratory medicine is an essential foundation for patient care, and without it, providers are not able to provide their patients with accurate and timely answers. Both our organizations are dedicated to building this foundation for the patients in the region,” says Mohamed Salama, M.D., chief medical officer for Mayo Clinic Laboratories.

Under the agreement, testing will be performed either at American Hospital Dubai or a Mayo Clinic Laboratories facility.

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