Royal Philips, a global leader in health technology, today announced late-breaking results of a large-scale, real-world analysis of U.S. Centers for Medicare & Medicaid Services (CMS) data on the rates of guideline adherence and associated mortality in patients with CIED infection . Results were presented at the American College of Cardiology’s 71st Annual Scientific Session by Sean Pokorney, M.D., Assistant Professor of Medicine at Duke University School of Medicine (U.S.) and member of the Duke Clinical Research Institute. The data demonstrated that approximately 4 in 5 patients are not treated according to HRS/EHRA Class I consensus recommendations and guidelines for CIED infection (full system extraction)[2,3]. Moreover, complete hardware removal (extraction) within 6 days was associated with a 42.9% lower risk of death compared with patients who did not undergo extraction.
The study examined 1,065,549 patients in Medicare in the USA who received a CIED between January 1, 2006 and December 31, 2019. Patients included in the CIED infection group were those that had an implant greater than 12 months old, had a primary diagnosis for infection of a device implant, and had documented antibiotic therapy. The study was an independent analysis conducted by Duke University and supported by a research grant from Philips. Philips had no role in the design or conduct of the analysis.
“This study highlights the life-threatening nature of device infections and the significant opportunities to improve care in these complex patients. The findings also emphasize the importance of timely diagnosis and complete treatment. Making things better for patients tomorrow will require working with clinicians across various specialties to advance education to help diagnose CIED infections and deliver timely care,” said Jonathan P. Piccini, MD., M.H.S., the lead investigator of the study, the Director of Cardiac Electrophysiology section at the Duke Heart Center. “The opportunity to ensure all patients have access to guideline-recommended care is not only imperative, but life-saving for patients across the world.”