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Researchers highlight the impact of COVID 19 pandemic on patients with cancer

New collaborative research from Queenโ€™s University Belfast, the University of Split, Croatia and Kingโ€™s College London has shown that the response to the outbreak of the coronavirus disease 2019 (COVID-19) is significantly affecting the treatment and care of patients with cancer.

The research, recently published in the European Journal of Cancer, highlights how the repurposing of health systems and implementation of social distancing measures, including national lockdowns, have had negative effects on patients with cancer. These effects included delays in urgent referrals and patients having their cancer treatment, such as chemotherapy postponed, or surgery being delayed.

Cancer is a common disease, with over 3.7 million new diagnoses in Europe each year and over 1.9 million deaths. The researchers highlight how this 1.9 million figure may increase significantly, directly as a result of the current crisis. Recent data from Wuhan in China, the original epicentre of the pandemic, shows that there has been a greater than 20% drop in the use of cancer drugs in the first quarter of 2020. The British Society of Gastroenterology also recommends that no endoscopic procedures, which are used to screen for bowel/colorectal cancer, can be performed for at least the next 3 months.

Professor Mark Lawler, Associate Pro-Vice-Chancellor and Professor of Digital Health, Queenโ€™s University Belfast, and Scientific Lead, DATA-CAN, the UK Health Data Research Hub for Cancer and Senior Author on the paper said: โ€œWe are already seeing the indirect effects of the COVID-19 crisis on cancer care. Urgent referral numbers are dropping, endoscopies and other surgical procedures are being postponed and many cancer specialists are being redirected to COVID-19 specific care. If we donโ€™t act, we risk the unintended consequence of the current COVID019 pandemic precipitating a future cancer epidemic.โ€

The research also highlights that as more people are worrying about the signs and symptoms of COVID-19, less people are seeking advice on new symptoms of a possible cancer, including abnormal bleeding or new lumps on the body.

Professor Eduard Vrdoljak, Department of Oncology, Clinical Hospital Centre Split, and the University of Split, Croatia and Lead Author on the paper said: โ€œI am extremely worried. We are experiencing significant challenges. Peopleโ€™s fear of attending any health facility, coupled with their minds being more focused towards COVID-19 symptoms, mean that they may down-play rectal or bladder bleeding, a lump in the breast or other signs of cancer that otherwise would lead them immediately to consult their doctor. We are starting to see people who may be at risk of developing cancer fearing a COVID-19 diagnosis more than a cancer diagnosis.โ€

Professor Richard Sullivan, Director of the Institute of Cancer Policy, Kingโ€™s College London and author on the paper said: โ€œThe focus on COVID-19 through 24-hour news cycle and social media, has dramatically changed our emotional and social infrastructure. At the scientific level, the modelling on which public health measures are being taken is entirely focused on COVID-19 mortality and morbidity, with little or no consideration for the impact of control measures on increasing morbidity and mortality in cancer, or indeed any other health condition.โ€

Margaret Grayson, Chair of the Northern Ireland Cancer Research Consumer Forum, said: โ€œPatients, especially cancer patients, are extremely worried at this difficult time. Governments and health systems need to reassure patients and citizens, but they also need to act, to ensure that the care of cancer patients is not compromised.โ€

Professor Vrdoljak added: โ€œIn transitioning nations in Central and Eastern Europe, and more widely in low- and middle-income countries globally, we are already significantly challenged in our fight against cancer. Letโ€™s not make the situation worse by ignoring cancer in the current crisis.โ€

Professor Lawler concludes: โ€œWe must encourage cancer patients, or citizens who are worried that they may have cancer symptoms, to continue to access health systems and we must ensure that those health systems are fit for purpose to support them. Cancer must be firmly in our cross wires, so that we avoid adding the lost lives of cancer patients to the COVID-19 death toll.โ€

ERT Delivers Actionable Insights to Identify COVID related Clinical Trial Risks

ERT Delivers Actionable Insights to Identify COVID related Clinical Trial Risks

Intuitive COVID-19 Dashboard highlights patient compliance risks to protect study outcomes

ERT, a global data and technology company that captures critical endpoint data while minimizing uncertainty and risk in clinical trials, announced new reporting capabilities that help clinical trial sponsors and CROs ensure high-quality data collection during current global stay-home mandates. The newly launched COVID-19 Dashboard integrates data on coronavirus infection rates in geographic areas surrounding study investigative sites, so sponsors can identify and proactively intervene where patient and site compliance to study protocols may be at risk.

In order to get high-quality data that demonstrates their compoundโ€™s efficacy and safety, sponsors need to ensure patients are completing self-reported assessments as directed by the study protocol. When patient compliance drops, data quality suffers, which puts clinical development programs at risk. Because of current pandemic-related restrictions limiting in-person patient access to investigative sites, the risk of patient non-compliance increases. To mitigate this risk, clinical trial sponsors need robust, easy-to-access tools to identify protocol compliance risks before they cause data quality problems.

ERTโ€™s COVID-19 Dashboard helps sponsors identify areas of imminent risk caused by reduced patient site visits, enabling them to intervene and keep patients engaged throughout clinical trials. The dashboard presents convenient views of COVID-19 cases in relation to study site locations, flags sites and patients with potential device/data risks, and enables a targeted intervention approach toward real-time study monitoring to ensure data quality, regardless of patient access to investigative sites.

โ€œWith the COVID-19 Dashboard, sponsors donโ€™t have to waste time searching multiple sources to identify data collection, correction, and transmission issues that could negatively impact data quality,โ€ said Otis Johnson, Ph.D., Vice President of Trial Oversight at ERT. โ€œOur proprietary cloud-based data management and analytics platform enables us to quickly deliver actionable insights and put important information at our customersโ€™ fingertips so they can easily identify problem areas and take action to maintain the integrity of their studies.โ€

Ideagen Offers Coronavirus Health and Safety Online Training Package Free to NHS Workers

Ideagen Offers Coronavirus Health and Safety Online Training Package Free to NHS Workers

Leading global provider of governance, risk and compliance software, UK company Ideagen Plc, has developed a special online training course, as part of its industry leading Q-Pulse Workrite package, to help remote workers during the coronavirus pandemic โ€“ and it is now offering this course to NHS workers free of charge.

Ideagenโ€™s CEO, Ben Dorks, said: โ€œThe Q-Pulse Workrite Coronavirus and Home Working online training course is aimed at everyone who is now having to work remotely. It covers advice on how to protect yourself from catching the virus, but also how to work safely at home to avoid developing physical and mental health conditions related to stress and working in an unusual environment.โ€

Q-Pulse Workrite is an established programme of courses that deal with DHSE (Department of Health, Safety Environment) and QHSE (Quality, Health, Safety and Environment) regulations. In light of the current situation Ideagenโ€™s developers have added a course specifically aimed at the challenges posed by the coronavirus pandemic.

A number of NHS Trusts are already clients of Ideagenโ€™s and it was one of these clients who sparked this latest initiative.

An NHS Clinical Scientist saw information about the new Q-Pulse Workrite course on LinkedIn and asked if it could be made available to NHS workers for free: โ€œThis would be massively helpful to our work,โ€ he said.

Ben commented: โ€œWhen we saw the post we were immediately inspired to see if we could make this happen and Iโ€™m delighted to say that we have successfully created a secure area that will enable NHS staff to log in and use this software free of charge.ย 

โ€œEveryone working in the NHS, whether on the front line or behind the scenes, is an absolute hero and we must all do everything we can to support them. We really hope by making this training free and available to all in the NHS we can help to keep them healthy and well while they are caring for the rest of us.โ€

Oxair’s life saving PSA systems can help boost oxygen supplies

Oxair's life saving PSA systems can help boost oxygen supplies

A potential worldwide shortage of medical oxygen supplies due to the coronavirus pandemic could be alleviated by installing Pressure Swing Adsorption (PSA) systems in healthcare facilities, says Oxair, a global manufacturer of advanced gas process systems.

Ensuring a reliable supply of oxygen during the Covid-19 crisis is proving challenging due to the rising demand from healthcare services across the world desperate to have the life-saving Oxygen for ventilators and masks to keep their growing number of patients alive, as well as to aid their recovery from the virus.

Australia-based Oxair and its manufacturing facility in both Australia and India can turn around orders for ready-to-use Oxygen PSA units in about 8 to ten weeks for the Asia/Pacific (APAC) and African regions, depending on local lockdown laws or travel restrictions. These are high quality, robust medical deice designed to last and deliver consistent, high purity oxygen on tap to hospitals and healthcare facilities even in the remotest locations around the world.

Medical facilities are often forced to rely on outsourcing this life-giving gas, with failing supplies a potential catastrophe for hospitals, not to mention the problems associated with the storage, handling and removal of traditional oxygen cylinders. PSA Oxygen offers better patient care with a permanent flow of high-quality oxygen โ€“ in this case a plug and play system with output pressure of four bars and a flow rate of 160 litres per minute, capable of piping oxygen around the hospital to every department as needed. Itโ€™s a highly cost-effective and hygienic alternative to the inconvenience and uncertainty of cylinders.

The system delivers constant oxygen of 94-95 percent purity through PSA filtration, a unique process that separates oxygen from compressed air. The gas is then conditioned and filtered before being stored in a buffer tank to be used directly by the end user on demand.

David Cheeseman of Oxair explained: โ€œWe are ready to step up supplies and prepared to do whatever is necessary to help healthcare services during the current coronavirus crisis – and beyond – by providing this life-saving oxygen equipment wherever it is needed. The design of these PSA systems as โ€˜plug-and-playโ€™ means that they are literally ready to start working as soon as they are delivered and plugged in โ€“ with voltage adapted to the country of delivery. So hospitals can rely on technology which is tried and tested over many years, coupled with almost instant access to vital oxygen supplies.โ€

Aboutย Oxair:

Oxair is an ISO 9001 certified company focused on the design and manufacture of packaged oxygen Pressure Swing Adsorption (PSA) Systems. Oxair manufactures very small, medium to large Oxygen PSA Tonnage plants.

Oxair also design and manufacture Nitrogen PSA systems up to 1000Nm3/hr. Theย Portfolio also includes designing Nitrogen systems from Air Products Membrane Technology whom we have forged strong links with over the past 20 years for Nitrogen and other gases.ย In addition, Oxair Design and Manufacture Heatless/Desiccant type Regeneration Dryers and filtration packages for a variety of industrial sectors including medical, gold mining, water treatment, oil & gas, food, chemical and biotech.

The dryers can be skid mounted or in a lifting frame certified for Off Shore lift if required. And also produce pressure vessels and skid fabrication and process piping, and the designs are focused on customer requirements of reliability, ease of maintenance, safety and plant self-protection.

How Intermittent Fasting Works And What Are Its Benefits

How Intermittent Fasting Works And What Are Its Benefits

Many people believe that eating breakfast, lunch, and dinner at the right time is critical to maintaining a healthy lifestyle. But, it doesn’t mean that you can’t modify this eating plan to help you reap more health benefits. Consider breaking the habit of eating in the morning, afternoon, and at night by implementing intermittent fasting in your daily diet.

Intermittent Fasting: An Overview

As its name implies, intermittent fasting is an eating pattern wherein you cycle between fasting and eating periods. At first, it may sound like the traditional eating habit of consuming the three standard meals in the morning, afternoon, and night. But, intermittent fasting requires practitioners to have longer fasting periods than eating hours.

Also, note that intermittent fasting doesnโ€™t restrict you with the foods you want to eat. So, you can still eat pizza or ice cream, but you need to follow certain guidelines to make the most out of this eating pattern.

One limitation to adhere to is your recommended daily calorie intake. For example, you need to consume 2,000 calories per day to maintain your weight. Consuming over 2,000 calories within your eating time will still make your intermittent fasting efforts ineffective.

Note that the extra calories consumed might become stored fat. Failure to convert those fat cells into energy may result in excess body fat, especially around the waist. Moreover, you still need to watch what you eat. Avoid fattening foods, like sugar-rich desserts, especially if youโ€™re living a sedentary lifestyle. Sugar, in particular, will go to the pancreas. Here, the organ secretes insulin, which is a hormone that returns the sugar into cells, like those in the liver and muscles.

If you follow a regular exercise routine, the body should have more energy to keep up with the physical activity, thanks to the energy provided by the sugar. Again, if the body doesnโ€™t get rid of this excess energy (which is the sugar), your system converts them into fat.

Therefore, always remember that intermittent fasting isnโ€™t a โ€œmagic pillโ€ thatโ€™ll make you achieve a lean body physique. You still need to follow specific guidelines to make this eating pattern work in your favor.

How Does Intermittent Fasting Work?

Know that several intermittent fasting methods exist, such as:

  • The 16:8 Method

Practitioners fast for 16 hours and eat within an eight-hour window in this intermittent fasting technique. For example, you fast between 8 pm to 12 pm, then, eat between 12 pm to 8 pm.

  • The 24-Hour Fast

As the name implies, intermittent fasting practitioners fast for 24 hours. But, this fasting window only occurs once or twice a week.

  • The 5:2 Diet

In this method, you would eat normally for five days a week. As for the other two days, you only consume about 500 to 600 calories.

  • The Warrior Diet

Be wary as the warrior diet should only be for intermittent fasting veterans. Donโ€™t attempt to adopt this technique if youโ€™re new to intermittent fasting because of its extreme procedures.

This eating plan involves following a low-calorie diet. An example meal would be a few servings of raw fruit and vegetables. Moreover, the eating window is only about four hours. Thus, you need to fast for 20 hours before you can grab a bite to eat.

Note that the rate at which you achieve positive results from intermittent fasting depends on the chosen technique. Itโ€™s because this eating plan happens in three stages, which are:

  • The Hypoglycemic Stage

First, the body starts to use its glucose or sugar reserves in the muscles and liver. As the blood sugar levels drop, the body experiences adverse reactions, like dizziness, drowsiness, and loss of balance.

Next, the body will try to avoid this state by attempting to produce additional glucose. But, if the glycogen, which is a substance deposited to tissues to store carbohydrates, is lacking, the body will, then, secrete other hormones, attempting to increase energy levels.

  • The Ketogenic State

The body achieves ketosis, a state in which the body has exhausted its glucose reserves. So, it turns to other potential energy sources, such as fat.

  • The Adapting Stage

In this final stage of intermittent fasting, the body adapts to the changes made. Hormone levels will regulate over time, and the benefits will start to manifest.

The Benefits Of Intermittent Fasting

Many benefits await intermittent fasting practitioners, provided you donโ€™t stray from a healthy diet. Some of these healthy advantages include:

  • Weight Loss

Weight loss is, perhaps, the primary reason for many people to start intermittent fasting. Since you’re going to eat within a reduced timeframe, you tend to eat fewer calories than usual.

Intermittent fasting may even lead to significant weight loss if paired with regular exercise. Remember that the body achieves ketosis through this eating plan. Hence, you can gain more energy to accomplish high-intensity training (HIIT) while burning extra fat in the process.

Moreover, intermittent fasting doesnโ€™t target a specific part of the body to convert fat into energy. Hence, youโ€™ll find the fat loss to be relatively equal throughout your system. It also means that you may have a higher chance of eliminating stubborn belly fat through intermittent fasting than doing 100 crunches every day.

  • Appetite Management

At first, it might be challenging to stay loyal to an intermittent fasting method. Not eating anything for an extended period can be taxing on the body and mind.

Note that intermittent fasting may come with some adverse effects at the beginning. Some of these side effects include:

  • Dizziness or light-headedness
  • Headache
  • Irritability
  • Lack of concentration
  • Nausea

Stick with the eating plan, and your body will adapt to the habit over time. You wonโ€™t find yourself getting too hungry as before. Moreover, hunger symptoms should begin to disappear after a few days.

In turn, you can suppress hunger pangs successfully, leaving you to continue with the intermittent fasting habit for as long as you want. Still, if you find yourself giving in to the temptation of eating during a fasting period, here are some quick tips to help you in that regard.

  • Drink lots of water
  • Meditate
  • Chew gum
  • Stay away from looking at food pictures
  • Go to sleep
  • Reduced Insulin And Glucose Levels

An intermittent fasting eating plan may also help regulate insulin and glucose levels.

Remember that the body breaks down carbohydrates, like sugary desserts, into glucose. Your system will, then, try to convert the glucose into additional energy, allowing you to last longer during high-intensity exercise sessions.

But, if you donโ€™t burn this excess glucose, the body converts the substance into fat. In turn, insulin levels drop, causing cells to release more glucose into the body, making you gain more fat and weight.

With intermittent fasting, the body will be in a regular state of ketosis. Hence, the body wonโ€™t have enough time to store excess fat, reducing insulin and glucose levels in the process.

Note that if the body has high amounts of insulin, you might be at risk of insulin resistance. This disorder makes the liver ignore or resist the signals that insulin is trying to release. The body will try to combat this ailment by releasing more insulin into your system, making the pancreas work harder than usual. Over time, the pancreas becomes worn out, which can lead to organ failure.

Moreover, insulin resistance might also become the precursor of type 2 diabetes. Itโ€™s because the body tends to store more glucose than necessary, creating opportunities for other health issues, like heart disease and stroke, to take place.

  • Stimulates Autophagy

Autophagy comes from the Greek words auto (self) and phagein (to eat). Therefore, the term means to eat oneself. It might sound gruesome, but note that autophagy is an intermittent fasting state wherein the body eliminates unnecessary substances that may otherwise require extra energy to maintain.

Intermittent fasting stimulates autophagy to clear old cellular parts, such as broken-down proteins. This process happens because the body becomes deprived of nutrition during the fasting stages. Your system may think that it canโ€™t sustain old cell parts, causing them to remove them.

In turn, the eating plan stimulates the development of new and better cellular components, causing the body to undergo a complete renovation from within.

In other words, intermittent fasting may help you create a better and healthier you from within, thanks to autophagy.

  • Reduced Inflammation

Inflammation is the bodyโ€™s defensive function that aids in the healing process. If your system detects an intruder, it responds by inflaming the affected area so as not to increase the risk of infections.

But, too much inflammation can also be dangerous. Some long-term health concerns associated with inflammation include:

  • Asthma
  • Tuberculosis
  • Rheumatoid arthritis
  • Sinusitis
  • Active hepatitis

Following a strict intermittent fasting habit may help lower inflammation as it reduces the oxidative stress in cells. As a bonus, the eating habit might be an effective solution to reducing inflammation caused by insulin resistance.

Key Takeaway

Ensure that you talk with a nutritionist or doctor before you begin any intermittent fasting method. Starting the eating plan without a proper strategy may lead to complications and, perhaps, even failure. But, if you do intermittent fasting correctly, you can reap several benefits, like reduced inflammation, reduced risk of insulin resistance, and increased weight loss.

NovaBay signs Agreement to Distribute COVID-19 Antibody Rapid Point-of-Care Test to U.S. Healthcare Professionals

NovaBay signs Agreement to Distribute COVID-19 Antibody Rapid Point-of-Care Test to U.S. Healthcare Professionals

NovaBay Pharmaceuticals, Inc. announces an agreement with Shenzhen Microprofit Biotech Co., Ltd. to become the exclusive U.S. distributor of a rapid, finger prick test to determine the presence of COVID-19 or a potential indication of antibody immunity to COVID-19. The fluorecareยฎ SARS-CoV-2 IgG & IgM Antibody Combined (colloidal gold chromatographic immunoassay) Test Kit is a point-of-care test to be administered by healthcare professionals. The test uses a drop of blood for the detection of COVID-19 antibodies with results available in approximately 10 minutes.

The fluorecare test kit has been validated through widely used RT-PCR testing to detect immunoglobulin M (IgM), which is the first antibody produced in response to initial exposure to the COVID-19 antigen, and immunoglobulin G (IgG), which provides a potential indication of antibody-based immunity to COVID-19. The fluorecare test kit has been ISO 13485 and CE Mark certified.

โ€œPublic health experts and leaders across our country are citing a critical need for mass testing and tracing procedures for those who are infected or have been infected with COVID-19 before reopening the nationโ€™s economy,โ€ said Justin Hall, NovaBay CEO. โ€œNasopharyngeal (back of the nose and throat) swabs for molecular detection are expensive and require laboratory testing that can lead to delays in obtaining results. Through a simple finger prick, IgG/IgM testing could provide for cost-effective detection of COVID-19 antibodies with results available in minutes as an important step in tracking the infection.

โ€œWe are delighted once again to work with our global health supplier network to secure a product that can help our communities during the COVID-19 pandemic and, subject to FDA clearance, we plan to offer the fluorecare test kit at very competitive pricing,โ€ he added.

NovaBay will submit the fluorecare test kit to the U.S. FDA under Emergency Authorization Use (EAU), which will be effective until the declaration that circumstances exist justifying the authorization of emergency use of in vitro diagnostic tests for detection and/or diagnosis of COVID-19 is terminated. The Company will also submit the fluorecare test kit for permanent FDA 510(k) clearance so that the test kit can continue to be used once the state of emergency has been declared over by the Federal Government. Because these test kits are one of the first few test kits of its kind to be reviewed by the FDA, NovaBay cannot assure a timeline for FDA review and/or clearance for commercial marketing of the fluorecare test kit in the U.S. under EAU or 510(k), or if clearance will be granted at all.

About NovaBay Pharmaceuticals, Inc.:
NovaBay Pharmaceuticals, Inc. is a biopharmaceutical company focusing on commercializing and developing its non-antibiotic anti-infective products to address the unmet therapeutic needs of the global, topical anti-infective market with its two distinct product categories: the NEUTROXยฎ family of products and the AGANOCIDEยฎ compounds. The Neutrox family of products includes AVENOVAยฎ for the eye care market, CELLERXยฎ for the aesthetic dermatology market, and NEUTROPHASEยฎ for wound care market.

Queen’s University leading clinical trial on cell therapy treatment for COVID19 patients

Queen's University leading clinical trial on cell therapy treatment for COVID19 patients

Researchers at Queenโ€™s University Belfast are leading a UK-wide clinical trial, offering an innovative cell therapy treatment for COVID-19 patients with acute respiratory failure.

This clinical trial, led by Professor Danny McAuley and Professor Cecilia Oโ€™Kane, both researchers from the Wellcome-Wolfson Institute for Experimental Medicine at Queenโ€™s, is investigating the use of allogenic Mesenchymal stromal cells (MSCs) in patients with a complication known as Acute Respiratory Distress Syndrome (ARDS) caused by COVID-19.

In the most critically unwell patients with COVID-19, many develop a complication known as ARDS. In ARDS the lungs become inflamed and leaky so they fill with fluid. This causes respiratory failure and patients may require admission to intensive care and a ventilator machine to support their breathing.

A recent statement from the four UK Chief Medical Officers outlined the importance of clinical trials amidst the COVID-19 crisis. Professor Cecilia Oโ€™Kane said: โ€œIt is only through clinical trials we will be able to determine if new treatments are effective and safe in critically ill patients.โ€

The trial involves the use of MSCs, a type of cell derived from human tissue such as bone marrow or umbilical cord (which is otherwise discarded after the baby is born), to treat the injury to the lung caused by COVID 19. MSCs are a novel treatment that have been shown in experimental models to reduce inflammation, fight infection and improve the repair of injured tissue.

Patients in this trial, which is known as REALIST COVID 19, will be treated with a purified population of MSCs derived from umbilical cord tissue called ORBCEL-C. The ORBCEL-C therapy has been developed by scientists at Orbsen Therapeutics in Galway, Ireland. The ORBCEL-C therapeutic is manufactured under licence by the UK NHS Blood and Transplant Service for the REALIST COVID-19 trial.

The trial is being introduced as part of an existing programme of research investigating the use of MSCs in patients with ARDS. The first patient has now been recruited with plans to recruit at least 60 patients throughout the COVID-19 pandemic at multiple sites across the UK including Belfast, Birmingham and London.

Professor Ian Young, Clinical Professor at the Centre for Public Health, Queenโ€™s University Belfast, Director of HSC R&D and Chief Scientific Advisor at the Department of Health, said: โ€œThe Health and Social Care Research & Development Division has been working with researchers across HSC to address the global problem of Coronavirus. We have contributed ยฃ230K for this vital research which will provide important evidence regarding a potential new treatment for respiratory failure, a leading cause of mortality in COVID-19. We will continue to support health research and encourage people to participate in research trials and other studies so patients can get the best possible treatment to help tackle the spread of COVID-19.โ€

The trial has been identified by the National Institute for Health Research (NIHR) as a national urgent public health study. It is one of a number of COVID-19 studies that have been given urgent public health research status by the Chief Medical Officer/ Deputy Chief Medical Officer for England. The study is funded by the Health and Social Care Research & Development Division and the Wellcome Trust, sponsored by the Belfast Health and Social Care Trust and supported by the NI Clinical Trials Unit, the NIHR Clinical Research Network and the Northern Ireland Clinical Research Network.

Orbsen CSO Steve Elliman noted: โ€œWhile there are over 100 vaccines and therapies in development targeting the SARS-CoV-2 infection – at present there are no disease modifying therapies approved for ARDS. Weโ€™re delighted the REALIST trial was approved and listed by NIHR as an Urgent Public Health Research Study so we can continue assess the safety of the ORBCEL-C therapy in patients with ARDS.โ€

Sir Professor Alimuddin Zumla of University College London, a global coronavirus and infectious diseases expert said: โ€œThis is an exciting and important trial which targets rectifying the underlying causes of lung damage and has great potential of saving many lives from COVID-19. The team should be congratulated for their leadership of host-directed therapies, a concept which has not yet been explored to its full potential.โ€

Professor Danny McAuley is also part of an international network of researchers who are taking forward trials of umbilical cord-derived Mesenchymal stromal cells for the treatment of COVID-19: UK: (UCL- Sir Professor Azumla); Portugal (Champualimud Foundation – Professor Markus Maurer; Italy (INMI-Professor Giuseppe Ippolito) and China (Fifth Medical Center- Professor Fu-Sheng Wang.)

UL Certifies Mobile Ultraviolet System for Large-Scale Healthcare Equipment Disinfection

UL Certifies Mobile Ultraviolet System for Large-Scale Healthcare Equipment Disinfection

UL leverages electrical and light technology expertise to support launch of ultraviolet-based technology solution for hospital and lab use.

UL, a leading global safety science company, todayย announced thatย 

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PurpleSun ,ย a healthcare technology companyย providing smart, light-based solutions for infection prevention,ย has receivedย theย first UL Certificationย forย aย large-scaleย mobileย ultravioletย disinfection system, theย PurpleSunย E300 Modular Paneling System.

Theย PurpleSunย E300ย was certified toย theย harmonizedย Standard, IEC 61010-1, 3rd Edition plus Amendment 1, theย standard for general safety requirements forย useย ofย electrical equipmentย used in laboratoriesย andย healthcare facilities.ย PurpleSun received certificationย after the E300 Modular Paneling System passedย extensiveย electricalย andย ultravioletย light emissionย testing,ย including risk mitigation analysis.

“Performance and safety testing is critical for successful patient care.โ€ฏย That’s why UL prioritizes safetyย whenย testing, inspectingย and certifyingย products and technologies,”ย saidย Deborah Jennings-Conner, engineering director, UL.ย ย “With this ULย Certification, we quickly leveragedย our expertise in electrical safety and light emissionsย whileย helpingย PurpleSun rapidlyย bring to market this solution toย help achieveย positive patient outcomes.”

PurpleSun’sย Ultravioletย Modular Paneling System, which can be deployed to various hospital areas, uses Focusedย Multivectorย Ultravioletย (FMUV)ย lightย โ€“ย focused light energy to improve germicidal effectiveness and speed โ€“ to quickly kill off organisms on medical and lab equipment.

Luis F. Romo, CEO and founder, PurpleSun, said, “Healthcare providers can have the peace of mind that the PurpleSun E300 meets and exceeds the strictest industry standards and helps ensure patient safety in the FMUV rapid treatment of equipment for the purpose of disinfection at the point of care. Our equipment plays a critical role in the fight against COVID-19. The UL Certification helps further complement our vision of sustainable impact to the quality of care for the healthiest patient-ready environments.”

According to the manufacturer, theย modular mobileย PurpleSunย unitย can be used to disinfect equipment in an operating room, hallway or patient roomย while staff continue to workย around the system. For example, the unitย canย be deployed toย quickly disinfect a stretcherย immediatelyย after patient use,ย alleviating the need to interrupt criticalย room and equipmentย downtimeย whileย promoting the health and safety of healthcare workers and patients.

“We are honored and privileged to be on the cutting edge of technologyย during this crisisย and help our hospital customers on the front lines advance care,ย all with the help from UL and its engineering teams,” said Romo.ย  “Withย theย Model E300,ย weย canย help healthcare providersย enhance safety for patients and caregiversย and,ย ultimately,ย save lives.”

About UL
UL helps create a better world by applying science to solve safety, security and sustainability challenges. We empower trust by enabling the safe adoption of innovative new products and technologies. Everyone at UL shares a passion to make the world a safer place. All of our work, from independent research and standards development, to testing and certification, to providing analytical and digital solutions, helps improve global well-being. Businesses, industries, governments, regulatory authorities and the public put their trust in us so they can make smarter decisions.

Cristal Standards Announces POSI-Check, an Easy to Implement Audit Solution for the Prevention of the Spread of Infection in the Hospitality Sector

Cristal Standards Announces POSI-Check, an Easy to Implement Audit Solution for the Prevention of the Spread of Infection in the Hospitality Sector

Cristal Standards, an Intertek company and market leading global health, safety, quality and security risk management business focused on the travel, tourism and hospitality sectors, has published a new audit solution to help in the Prevention of the Spread of Infection (POSI). The POSI-Check audit solution is designed to formulate and monitor an effective response to communicable infections in hotels and restaurants around the world.

POSI-Check was created to support organisations over the coming months as the world recovers from the COVID-19 pandemic. The POSI-Check solution guides hoteliers and restaurants to demonstrate they are effectively managing the prevention of spread of infection. An easy to implement solution, it provides the tools needed to maintain a level of POSI control in any environment to give guestsโ€™ assurance that their health and safety is of utmost importance.

Dedicated total quality assurance experts will work with the staff and management teams to implement the POSI protocols in a facility. Certification will be earned through hands on training sessions, bi-monthly auditing, and easy-to-use swab tests to detect adenosine triphosphate (ATP) of key surfaces in public common areas such as toilet and bathrooms, bars and dining areas, reception and concierge desks, elevators and escalators, gym and leisure facilities.

โ€œAs leaders in health, safety, and quality to the hospitality industry we understand the ongoing impact this will have on our clients. POSI-Check will help to ensure your staff is complying with necessary measures in order to prevent the spread of infection, while assuring your guests that their welfare is top priority says Cristal Standards CEO, Stephen Tate. โ€œPOSI-Check was designed to help our hospitality partners prepare to ensure the safety of their staff and guests as the world resumes travel post-COVID19.โ€

With the travel and tourism sector contributing $8.8 trillion to the global economy* and outpacing the growth rate of world GDP, consumer awareness and concerns in relation to health, hygiene, safety and security when travelling have increased significantly due to the rapid spread of the COVID-19 pandemic. The potential reputational damage for hotels caused by poor hygiene safety and security standards, combined with greater regulation and compliance requirements imposed by governments in tourist destinations, has seen more importance placed upon the need for bespoke, innovative outsourced Quality Assurance solutions.

POSI-Check was designed to complement other Cristal Standards modules including FoodCheck, DineCheck, and RoomCheck which help our clients identify, prioritise and effectively manage risk over multiple disciplines whilst allowing them to focus on delivering the promises associated with their brand. The POSI-Check module is currently available in English, Spanish, French, Arabic, Turkish, Greek, and Portuguese.

Intertekโ€™s Cristal Standards solutions are suitable for all hospitality industries including food establishments such as bakeries, restaurants, hotels, catering, fast food chains, coffee shops, and retail and luxury stores. By partnering with Intertek, your establishments will benefit from our global network with experts using unique principles to evaluate sites on a global scale with a standard comparison benchmark. Intertek provides the right set of tools and inspections, to provide total quality assurance to all its customers.

About Intertek

Intertek is a leading Total Quality Assurance provider to industries worldwide. Our network of more than 1,000 laboratories and offices and over 46,000 people in more than 100 countries, delivers innovative and bespoke Assurance, Testing, Inspection and Certification solutions for our customersโ€™ operations and supply chains. Intertek Total Quality Assurance expertise, delivered consistently with precision, pace and passion, enabling our customers to power ahead safely.

CELLINK launches a real-time qPCR instrument

CELLINK launches a real-time qPCR instrument

CELLINK has started reselling a qPCR instrument. The instrument uses aย laboratory techniqueย ofย molecular biologyย based on theย polymerase chain reaction.ย It monitors the amplification of a targetedย DNAย molecule during the PCR (i.e., in real time).

qPCR is a proven and stable technology with numerous applications. It is commonly used for both diagnostic and basic research. Uses of the technique in the industry include the quantification of microbial load in foods, the detection of GMOs (genetically modified organisms) and the quantification and genotyping of human viral pathogens such as SARS-CoV-2. The unit includes dual channels and is open source, allowing users to use any kit to run their samples. It is designed as a high-quality, low-throughput qPCR cycler. The instrument is easy to use and runs a sample in 20-40 minutes. CELLINK wants to help provide scientists with the tools they need to make a difference and therefore offers this instrument at a low-cost point to help advance research related to the COVID-19 pandemic.

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