Emerging Therapies in Hair Transplantation PRP and Stem Cell Applications


Hair loss is a prevalent concern affecting millions worldwide, transcending age, gender, and ethnicity. The emotional impact of hair loss can be significant, whether due to genetics, aging, hormonal imbalances, or environmental factors.

Traditional hair transplantation methods, such as Follicular Unit Transplantation (FUT) and Follicular Unit Extraction (FUE), have proven effective in restoration. In a few recorded cases, FUE has achieved 90% long hair retrieval and a 3–4% graft attrition rate. However, as medicine evolves, researchers and practitioners have explored novel approaches to optimize outcomes and enhance patient experiences.

In recent years, two cutting-edge therapies have gained considerable attention in hair transplantation – platelet-rich plasma (PRP) therapy and stem cell applications. However, these have to be combined with FUT or FUE and can’t be used independently for hair transplantation.

Platelet-Rich Plasma (PRP) Therapy in Hair Transplantation

Platelet-rich plasma (PRP) therapy has garnered significant attention as a potential breakthrough in hair transplantation. It was initially used in sports medicine and orthopedics for its regenerative properties.

In fact, PRP has been used for various medical benefits, and hair loss prevention or help recovering from hair transplantation are its new applications. The use of PRP in multiple treatments is so high that the global PRP market size stood at $627.9 million in 2022.

The treatment for hair transplantation involves the extraction and concentration of platelets from the patient’s blood. These are then injected directly into the scalp at areas experiencing hair loss.

According to Hair Transplants New York, PRP therapy for hair loss is a 3-step procedure as listed below:

  • Plasma is ejected from your body.
  • It is purified.
  • It is injected into the scalp.

The website states that PRP can be utilized as a standalone therapy for early-stage hair loss or as an adjunct to traditional hair transplantation procedures like FUT or FUE. When combined, PRP is typically administered before or after the hair transplant surgery.

Pre-transplant PRP can strengthen existing hair follicles and improve the overall health of the scalp, while post-transplant PRP can aid in faster healing and enhance graft survival.

The underlying mechanism of PRP’s hair growth potential lies in its ability to enhance the activity of hair follicles. The growth factors present in PRP promote blood vessel formation and stimulate the proliferation of dermal papilla cells, essential for hair follicle growth and regeneration. Additionally, PRP helps reduce scalp inflammation, which can further contribute to hair regrowth.

How to Go Ahead With Using PRP for Hair Loss

Consulting with a qualified medical professional in your locality is crucial before considering PRP for hair loss treatment. They will assess your specific condition, medical history, and suitability for PRP therapy. You should look for a reputable doctor in your locality.

Many people from the US, like New Yorkers or Californians, go to Middle Eastern countries, especially Turkey, for hair transplants. Male hair transplant surgery is a whopping $1 billion industry in Turkey.

However, hair transplant surgeries without proper consultation can fail. People don’t realize that they should first consult with a local doctor. So, for instance, you live in New York City (NYC). In that case, you should consult a hair loss doctor in NYC. They will be able to help you understand whether you need a hair transplant surgery or the hair loss is at the initial stages and can be prevented with treatment options like PRP.

The next step is to discuss the expected results. Your doctor will provide you with realistic expectations about the potential outcomes of PRP therapy. Individual results can vary, and not everyone experiences significant hair regrowth. It’s essential to clearly understand the potential benefits and limitations of the treatment.

You should also ask your doctor to thoroughly explain the PRP hair restoration process. You can consult with a PRP hair restoration specialist in your area. For instance, considering the same example above, you can look for doctors specializing in PRP hair restoration in New York. This should allow you to understand how to proceed with your hair loss problem.

Stem Cell Applications in Hair Transplantation

Stem cells, known for their unique regenerative capabilities, have the potential to revolutionize hair restoration by stimulating the growth of new hair follicles and rejuvenating existing ones.

In hair transplantation, stem cells are harnessed for their regenerative properties, making them valuable in promoting hair growth and combating hair loss. Understanding the fundamental mechanisms stem cells influence hair regeneration is essential for grasping their potential applications.

Various types of stem cells can be employed in hair restoration procedures. Mesenchymal stem cells (MSCs) and adipose-derived stem cells (ADSCs) are among the most widely studied for their hair growth potential. These cells can differentiate into dermal papilla cells, which are crucial in hair follicle development and cycling.

Comparative Analysis: PRP vs. Stem Cell Therapy

PRP and stem cell therapy have both gained prominence in hair transplantation. Hence, it becomes essential to conduct a comparative analysis to understand their respective strengths, limitations, and suitability for different types of hair loss.

While PRP primarily relies on growth factors and cytokines to stimulate existing hair follicles, stem cell therapy can regenerate new hair follicles. Comparing the long-term results of these treatments will shed light on their sustainability and lasting benefits.

Certain types of hair loss may respond better to PRP or stem cell therapy based on their underlying causes. For instance, different therapies can work for different medical conditions, such as androgenetic alopecia, alopecia areata, and traction alopecia. According to a recent study published in the Stem Cells Journals, stem cell therapy best suits androgenetic alopecia treatment.

Another crucial aspect you should consider when selecting which hair transplant method is right for you is finance. Assessing the cost of PRP and stem cell therapy, including initial treatment expenses and potential follow-up sessions, will help patients understand the financial implications of each option.


It is crucial to emphasize that no one-size-fits-all solution in hair transplantation exists. Each patient’s unique hair loss pattern, donor area characteristics, medical history, lifestyle, and treatment expectations must be thoughtfully considered when making treatment decisions. Personalization and individualization remain the guiding principles for successful and satisfactory outcomes.