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What Drugs Do with a Brain?

The brain is a complex body organ. It comprises a three-pound white and gray matter mass that is at the center of human activity. Essentially, a person needs the brain to do everything. For instance, a person needs the...

Mount Sinai Discovers New Drug Combo to Induce High Rates of Human Beta Cell Regeneration

Researchers at the Icahn School of Medicine at Mount Sinai have discovered a novel combination of two classes of drugs that, together, cause the highest rate of proliferation ever observed in adult human beta cells—the cells in the pancreas...

Much shorter radiation treatment found to be safe, effective for people with soft tissue sarcoma

A new study led by researchers at the UCLA Jonsson Comprehensive Cancer Center found that treating soft tissue sarcoma with radiation over a significantly shorter period of time is safe, and likely just as effective, as a much longer...

Investigational Subcutaneous Formulation of Vedolizumab Achieves Clinical Remission at Week 52 in Patients with Moderately to Severely Active Crohns Disease

Takeda Pharmaceutical Company Limited announced results from the phase 3 VISIBLE 2 clinical trial evaluating the efficacy and safety of an investigational subcutaneous (SC) formulation of the gut-selective biologic vedolizumab (Entyvio®) for use during maintenance therapy in adult patients...

Imminence of New Gonorrhea Therapeutic Drugs is Evident as the Bacteria Grow Super Resistant to Antibiotics

According to a new study, the gonorrhea therapeutics market will reach US$ 970 Mn in 2019, and estimated to register a 4% Y-o-Y over 2018. The gonorrhea therapeutics industry will remain influenced by increased attention on new developments in...

Road to Cell Death More Clearly Identified for Parkinson’s Disease

A pathway toward cellular death named for Thanatos identified by researchers as a key driver of nerve cell degradation in Parkinson’s disease Dopamine neurons are the primary cell type targeted by Parthanatos in Parkinson’s disease. Credit: The Dawson Lab In experiments...

Specific CD8 T cell states may indicate response to immune checkpoint therapy for melanoma

A multi-institutional research team, led by investigators at Massachusetts General Hospital (MGH) and the Broad Institute of MIT and Harvard, has identified specific states of cytotoxic CD8 T cells that are associated with patient response to checkpoint immunotherapy for...

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