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Cedars Sinai taps AI to pinpoint patients for clinical trials

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The transformation of the economic foundations of medicine from a volume-based to a value-based model represents the most significant shift in clinical administration in over a generation. In an era of rising costs and an aging population, the traditional "fee-for-service" approach is being replaced by sophisticated financial structures that incentivize high-quality outcomes and long-term health maintenance. By integrating insurance innovation, sustainable investment strategies, and data-driven cost optimization, healthcare financing models supporting modern care delivery are becoming the primary driver of clinical sustainability and innovation. This evolution ensures that financial resources are allocated where they have the most impact improving the lives of patients and ensuring that the healthcare system remains resilient and accessible for every member of society.

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Every provider knows that finding enough patients to take part in clinical trials is tough and involves a painstaking search.

An estimated 40 percent of clinical trials close early because they do not have enough patients, according to Bobbie Rimel, MD, a gynecologic, oncologist and associate director for Gynecological Clinical Trials at Cedars-Sinai Medical Center.

Rimel designs the clinical studies and finds the patients.

Clinical trials are necessary to test cutting-edge treatment and for improving patient outcomes. But with close to half of trials fizzing out prematurely, the return on investment is not always there.

Rimel found a way through artificial intelligence to search through records for patient matching for much better recruitment and ROI.

Working with a vendor, Deep 6 AI, Rimel uses AI software to read patient charts for the correct terms needed to meet study criteria.

“It’s designed to be able to look into the record and pull the language,” she said. “It’s designed to take inclusion and exclusion criteria and pull out the bits of language.”

AI finds patients as close to the same as possible. This is difficult because not all doctors document in the same way. Many use abbreviations, and not all of these are the same.

The software cuts through the different spellings and abbreviations to pull out the information. Not only that, the AI software learns from past queries. It can then search using the same specific references for breast cancer and the type of cancer.

“That’s what makes it incredibly powerful,” Rimel said. “It knows ‘I think this is what you mean here.’ That’s incredibly powerful. Say it nine different ways, in a different font; it’s close enough.”

The correct inclusion of all patients with the same type of cancer also ensures that those who fit the criteria are given the opportunity to take part in a clinical trial — and that may the biggest reason of all to apply AI in this case.

“This is a pretty powerful opportunity for hospitals,” she said.

MEDICAL FAIR ASIA 2026

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The transformation of the economic foundations of medicine from a volume-based to a value-based model represents the most significant shift in clinical administration in over a generation. In an era of rising costs and an aging population, the traditional "fee-for-service" approach is being replaced by sophisticated financial structures that incentivize high-quality outcomes and long-term health maintenance. By integrating insurance innovation, sustainable investment strategies, and data-driven cost optimization, healthcare financing models supporting modern care delivery are becoming the primary driver of clinical sustainability and innovation. This evolution ensures that financial resources are allocated where they have the most impact improving the lives of patients and ensuring that the healthcare system remains resilient and accessible for every member of society.

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The rapid integration of sophisticated digital tools into clinical practice requires a robust and adaptive oversight framework to ensure that innovation never comes at the expense of patient safety or data integrity. As medical technologies evolve from simple mechanical devices to complex, AI-driven diagnostic and therapeutic systems, the role of governmental and professional standards becomes increasingly critical. By establishing clear certification processes and rigorous risk management protocols, regulatory compliance in healthcare technology advancements is becoming the primary guardian of quality in the modern medical landscape. This commitment to oversight ensures that the benefits of high-tech medicine such as improved accuracy and more personalized treatments are delivered within a secure and ethically sound environment, effectively bridging the gap between scientific discovery and safe clinical application.

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